Zemede Zale, Tariku Befikadu, Kote Mesfin, Estifanos Wubshet
Arba Minch Zuria District Health Office , Arba Minch, Ethiopia.
Department of Public Health, Arba Minch University, Arba Minch, Ethiopia.
HIV AIDS (Auckl). 2019 Jul 1;11:147-154. doi: 10.2147/HIV.S200120. eCollection 2019.
Undernutrition constitutes an important threat to the success of HIV programs in sub-Saharan Africa, and failure to effectively address it may jeopardize the benefits gained so far in the fight against HIV. The aim of the study was to assess undernutrition and associated factors among HIV-positive adult patients enrolled in antiretroviral therapy (ART) clinics in Arba Minch area, south Ethiopia. A facility-based cross-sectional study was conducted in 2017. There were 351 adult individual study participants who were enrolled in ART clinics in Arba Minch area public health facilities. Variables with -value less than 0.25 on binary logistic regression analysis were entered into a multivariate logistic regression model to outline the independent predictors of undernutrition. CI of 95% was used to assess precision of the study. Out of all the participants, 18.23% (95% CI: 14.52-22.65) were undernourished. The prevalence of undernutrition was significantly lower among those consuming food from five or more food groups per day (AOR: 0.33; 95% CI: 0.16-0.71) and undergoing ART for more than a year (AOR: 0.24; 95% CI: 0.08-0.73). On the contrary, the prevalence was significantly higher among those who were currently smoking tobacco (AOR: 6.67; 95% CI: 1.45-30.76). In addition, those with WHO clinical stage 3 had a significantly higher prevalence of undernutrition compared to those with WHO clinical stage 1 (AOR: 311; 95% CI: 1.47-6.60). The prevalence of undernutrition was high among adults with HIV/AIDS enrolled in ART clinics in the study area. The prevalence of undernutrition was lower among those who consumed diverse food groups and had been receiving ART for longer (more than a year). On the contrary, the prevalence of undernutrition was higher among those who consumed tobacco and with higher WHO clinical stage. Therefore, efforts should be made to enhance the dietary diversity of these individuals.
营养不良对撒哈拉以南非洲地区艾滋病项目的成功构成了重大威胁,未能有效解决这一问题可能会危及到目前在抗击艾滋病方面所取得的成效。本研究的目的是评估埃塞俄比亚南部阿尔巴明奇地区接受抗逆转录病毒治疗(ART)的成年艾滋病病毒阳性患者中的营养不良情况及相关因素。2017年开展了一项基于机构的横断面研究。共有351名成年个体参与了阿尔巴明奇地区公共卫生机构的抗逆转录病毒治疗门诊的研究。在二元逻辑回归分析中P值小于0.25的变量被纳入多变量逻辑回归模型,以确定营养不良的独立预测因素。采用95%置信区间(CI)来评估研究的精确性。在所有参与者中,18.23%(95%CI:14.52 - 22.65)存在营养不良。每天食用五种或更多食物组的人群以及接受抗逆转录病毒治疗超过一年的人群中,营养不良的患病率显著较低(调整后比值比[AOR]:0.33;95%CI:0.16 - 0.71)。相反,目前吸烟的人群中患病率显著较高(AOR:6.67;95%CI:1.45 - 30.76)。此外,与世界卫生组织临床分期为1期的患者相比,临床分期为3期的患者营养不良患病率显著更高(AOR:3.11;95%CI:1.47 - 6.60)。在研究地区接受抗逆转录病毒治疗门诊的成年艾滋病病毒/艾滋病患者中,营养不良的患病率较高。食用多种食物组且接受抗逆转录病毒治疗时间较长(超过一年)的人群中,营养不良的患病率较低。相反,吸烟人群以及世界卫生组织临床分期较高的人群中,营养不良的患病率较高。因此,应努力提高这些人群的饮食多样性。