Indoor Environment Group, Lawrence Berkeley National Laboratory, Berkeley, CA.
Indoor Air. 2019 Nov;29(6):895-902. doi: 10.1111/ina.12588. Epub 2019 Aug 5.
This paper provides meta-analyses of the published findings relating the respiratory health of occupants of schools with visible dampness, water damage, visible mold, and/or mold odor. Random effects models were used to develop central estimates and confidence limits for the associations of respiratory health effects with school dampness and mold. Eleven studies, all with cross-sectional designs, were included in the meta-analyses; however, analyses for some health outcomes were based on as few as four studies. Analyses were performed using data from adults and children combined, using only data from children, and using data from adults and children after excluding two studies. The central estimates of odds ratios from the meta-analyses were consistently above unity. The evidence of adverse health effects was strongest for cough and wheeze, which had confidence limits excluding unity in some or all analyses. The odds ratios of 1.32 for cough and 1.68 for wheeze suggest moderate increases in health risk. Studies not included in the meta-analyses provide additional evidence that dampness and mold in schools are associated with adverse health outcomes. These meta-analyses and the published literature not included in the meta-analyses suggest that dampness and mold in schools are associated with adverse respiratory health effects.
本文对已发表的文献进行了荟萃分析，这些文献涉及学校可见潮湿、水损坏、可见霉菌和/或霉菌气味与学生呼吸健康之间的关系。采用随机效应模型来确定呼吸健康影响与学校潮湿和霉菌之间关联的中心估计值和置信区间。11 项研究均采用横断面设计，其中一些健康结果的分析仅基于 4 项研究。分析结合了成人和儿童的数据进行，仅使用儿童的数据进行，以及在排除两项研究后，同时使用成人和儿童的数据进行。荟萃分析的中心估计比值始终大于 1。有证据表明，咳嗽和喘息的健康影响最为明显，在某些或所有分析中，置信区间排除了 1。咳嗽的比值比为 1.32，喘息的比值比为 1.68，表明健康风险略有增加。未纳入荟萃分析的研究提供了更多证据表明，学校潮湿和霉菌与不良健康结果有关。这些荟萃分析和未纳入荟萃分析的已发表文献表明，学校潮湿和霉菌与不良呼吸健康影响有关。
