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巨细胞动脉炎相关慢性前部缺血性视神经病变黄斑区的光学相干断层扫描血管造影

Optical Coherence Tomography Angiography of Macula in Chronic Anterior Ischaemic Optic Neuropathy Associated with Giant Cell Arteritis.

作者信息

Mahdjoubi Amir, Haouas Maher, Caliot Jessy, Jaillant Romain, Idlefqih Wafa, Amari Fatima Zohra, Chahed Sadri

机构信息

Ophthalmology Department, Hôpital Victor Dupouy, Argenteuil, France.

Ophthalmology Department, Hôpital Simone Veil, Eaubonne, France.

出版信息

Neuroophthalmology. 2018 Jul 18;43(3):192-195. doi: 10.1080/01658107.2018.1488175. eCollection 2019 Jun.

Abstract

A 74-year-old man presented with bilateral optic nerve atrophy related to arteritic anterior ischaemic optic neuropathy (AION) which started 22 years ago. Atrophic papilla was noted in both eyes and optical coherence tomography showed thinning of the retinal nerve fibres layer as well as the macular ganglion cell complex. Optical coherence tomography angiography of the macula found a decreased density of the superficial capillary complex, whereas deep capillary complex was well-preserved. Inner retinal layer atrophy in chronic arteritic AION is followed by a loss of vascularisation in these layers as a consequence of the neurodegeneration.

摘要

一名74岁男性患者,患有与22年前开始的动脉炎性前部缺血性视神经病变(AION)相关的双侧视神经萎缩。双眼均可见萎缩性视乳头,光学相干断层扫描显示视网膜神经纤维层以及黄斑神经节细胞复合体变薄。黄斑光学相干断层扫描血管造影发现浅表毛细血管复合体密度降低,而深部毛细血管复合体保存良好。慢性动脉炎性AION中的视网膜内层萎缩之后,由于神经退行性变,这些层中的血管化会丧失。

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Changes in macular layers in the early course of non-arteritic ischaemic optic neuropathy.非动脉炎性缺血性视神经病变早期黄斑层的变化
Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):561-7. doi: 10.1007/s00417-015-3066-3. Epub 2015 May 28.

本文引用的文献

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Giant cell arteritis: ophthalmic manifestations of a systemic disease.巨细胞动脉炎:一种全身性疾病的眼部表现
Graefes Arch Clin Exp Ophthalmol. 2016 Dec;254(12):2291-2306. doi: 10.1007/s00417-016-3434-7. Epub 2016 Aug 5.
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Ocular manifestations of giant cell arteritis.巨细胞动脉炎的眼部表现。
Am J Ophthalmol. 1998 Apr;125(4):509-20. doi: 10.1016/s0002-9394(99)80192-5.

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