Trachuk Polina, Marin Saquicela Tania, Levi Michael, Khedimi Rabea
Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, United States.
Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, United States.
IDCases. 2019 May 31;17:e00569. doi: 10.1016/j.idcr.2019.e00569. eCollection 2019.
is an uncommon cause of brain abscesses. Immunocompromised hosts, pregnant women and patients at extremes of age are especially susceptible. We discuss the successful management of a woman with autoimmune hepatitis on prednisone and azathioprine therapy with a brain abscess. Previously thought to be a rare cause of central nervous system (CNS) infection, the incidence of CNS listeriosis has increased due to a rise in organ and bone marrow transplantation requiring immunosuppressive medications. brain abscesses are now more frequently described and are associated with high rates of concomitant bacteremia suggesting a hematogenous route of infection.
是脑脓肿的一种罕见病因。免疫功能低下的宿主、孕妇和年龄极端的患者尤其易感。我们讨论了一名正在接受泼尼松和硫唑嘌呤治疗的自身免疫性肝炎女性患者合并脑脓肿的成功治疗案例。中枢神经系统李斯特菌病以前被认为是中枢神经系统（CNS）感染的罕见病因，由于器官和骨髓移植需要使用免疫抑制药物，其发病率有所上升。现在脑脓肿的描述更为频繁，且与高比例的合并菌血症相关，提示感染途径为血行感染。
