从 （Mill.）Swingle 的根皮中分离出的苯丙素类化合物的鉴定。
The identification of phenylpropanoids isolated from the root bark of (Mill.) Swingle.
机构信息
School of Traditional Chinese Materia Medica, Key Laboratory of Computational Chemistry-Based Natural Antitumor drug Research & Development, Liaoning Province, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.
Chinese People's Liberation Army Logistics support force No.967 Hospital, Dalian, People's Republic of China.
出版信息
Nat Prod Res. 2021 Apr;35(7):1139-1146. doi: 10.1080/14786419.2019.1643861. Epub 2019 Jul 17.
Chemical investigation of 75% EtOH exact of the root bark of (Mill.) Swingle led to the isolation and identification of two new phenylpropanoids (-), along with six known compounds (-). Their chemical structures were elucidated by extensive spectroscopic data analyses including NMR experiments and HRESIMS analyses, as well as computer-assisted structure elucidation software (ACD/Spectrus Processor). All compounds were evaluated for cytotoxic activities against Hep 3B and Hep G2 cells. Compound and displayed weak cytotoxic activities against the Hep 3B cell line.
对（Mill.）Swingle 的根皮的 75%EtOH 提取物进行化学研究，分离并鉴定了两种新的苯丙素（-），以及六种已知化合物（-）。通过广泛的光谱数据分析，包括 NMR 实验和 HRESIMS 分析以及计算机辅助结构解析软件（ACD/Spectrus Processor），阐明了它们的化学结构。所有化合物均对 Hep 3B 和 Hep G2 细胞进行了细胞毒性活性评估。化合物和对 Hep 3B 细胞系表现出微弱的细胞毒性活性。
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