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胸壁下脓肿——病例报告及文献综述

Empyema Necessitatis-A Case Report and Review of the Literature.

作者信息

Ellebrecht David B, Pross Moritz M F, Schierholz Stefanie, Palade Emanuel

机构信息

Department of Surgery, University Medical Center Schleswig-Holstein, Luebeck, Germany.

Department of Orthopedics and Trauma Surgery, Robert Bosch Hospital, Stuttgart, Germany.

出版信息

Surg J (N Y). 2019 Jul 16;5(2):e57-e61. doi: 10.1055/s-0039-1693653. eCollection 2019 Apr.

Abstract

Pleural empyema necessitatis caused by is a rare but severe infection. predominantly and represent the second most common pathogen for empyema necessitans after mycobacteria. The incidence is reported in the literature to be 1:300,000. Men are thrice more likely to be affected than women. Pathogenetically, an infection can be triggered by aspiration in immunocompromised individuals which leads to an atelectasis with pneumonitis. In two cases, a 38-year-old construction worker and a 61-year-old woman with ulcerative breast carcinoma, who presented to the local emergency department with a painful swelling of the left chest, diagnostic workup revealed a pleural empyema necessitatis of the left chest. An antibiotic treatment was initiated with piperacillin/tazobactam and sulbactam/ampicillin, respectively. Temporally vacuum-dressing therapy was initiated after surgical debridement. In the course of the procedure, a reconstruction of tissue damage was feasible. The patients were recovered completely and discharged with an oral antibiotic treatment (amoxicillin) for 6 and 12 months, respectively. Thoracic actinomycosis is a relatively uncommon and traditionally chronic, indolent infection secondary to pulmonary infection with . Surgical treatment is generally reserved for cases failing to resolve with antibiotic therapy. Early diagnosis, prompt debridement, and narrow spectrum β-lactam antibiotics can result in complete resolution of infection and good prognosis.

摘要

由[未提及具体病因]引起的胸膜坏死性脓胸是一种罕见但严重的感染。[未提及具体病原体]主要[未提及具体情况],是继分枝杆菌之后胸膜坏死性脓胸的第二常见病原体。文献报道其发病率为1:300,000。男性受影响的可能性是女性的三倍。从发病机制来看,免疫功能低下个体的误吸可引发感染,进而导致肺不张伴肺炎。在两例病例中,一名38岁的建筑工人和一名患有溃疡性乳腺癌的61岁女性因左胸疼痛肿胀到当地急诊科就诊,诊断检查发现左胸胸膜坏死性脓胸。分别开始使用哌拉西林/他唑巴坦和舒巴坦/氨苄西林进行抗生素治疗。手术清创后开始进行临时负压敷料治疗。在手术过程中,组织损伤的修复是可行的。患者完全康复,分别接受了为期6个月和12个月的口服抗生素(阿莫西林)治疗后出院。胸段放线菌病是一种相对罕见的、传统上为慢性、隐匿性的感染,继发于肺部感染[未提及具体病原体]。手术治疗一般适用于抗生素治疗无效的病例。早期诊断、及时清创和使用窄谱β-内酰胺抗生素可使感染完全消退并预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a22c/6635108/3a17daebdeb9/10-1055-s-0039-1693653-i1800036oa-1.jpg

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