de Moares Michelle Bianchi, Barbier Winnie Souza, Raldi Fernando Vagner, Nascimento Rodrigo Dias, Dos Santos Lúcio Murilo, Loureiro Sato Fábio Ricardo
Assistant Professor, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
DDS Student, Oral and Maxillofacial Surgery Area, Department of Diagnosis and Surgery, College of Dentistry, State University of São Paulo, São José dos Campos, Brazil.
J Oral Maxillofac Surg. 2019 Nov;77(11):2258.e1-2258.e8. doi: 10.1016/j.joms.2019.06.001. Epub 2019 Jun 19.
The objective of the present study was to compare 3 sedation protocols using diazepam, midazolam, and nitrous oxide.
A total of 120 patients with an indication for extraction of third molars were selected. All 120 patients had had moderate to severe levels of anxiety according to the Corah Dental Anxiety Scale. The patients were randomly divided into 3 groups. The patients' vital signs were measured, and the results analyzed by descriptive statistical analysis and statistical tests of comparison.
No statistically significant differences were found in the patients' heart rate. However, the differences in the systolic and diastolic blood pressure were statistically significant after 15 minutes of nitrous oxide sedation. The oximetry data showed no differences among the 3 sedation protocols. We also found no statistically significant differences in the retrograde amnesia test. The differences in anxiety from preoperatively to postoperatively were statistically significant for all techniques, demonstrating their effectiveness in anxiety control.
All 3 preoperative sedation techniques for anxious patients undergoing extraction of third molars used in the present study were effective in controlling the anxiety, with little effect on the patients' vital signs and retrograde amnesia.
本研究的目的是比较使用地西泮、咪达唑仑和一氧化二氮的三种镇静方案。
共选择了120例有拔除第三磨牙指征的患者。根据科拉牙科焦虑量表，所有120例患者均有中度至重度焦虑水平。患者被随机分为3组。测量患者的生命体征，并通过描述性统计分析和比较统计检验对结果进行分析。
患者心率未发现统计学上的显著差异。然而，一氧化二氮镇静15分钟后，收缩压和舒张压的差异具有统计学意义。血氧饱和度数据显示三种镇静方案之间没有差异。我们在逆行性遗忘测试中也未发现统计学上的显著差异。所有技术术前至术后的焦虑差异均具有统计学意义，表明它们在控制焦虑方面的有效性。
本研究中用于焦虑患者拔除第三磨牙的所有三种术前镇静技术在控制焦虑方面均有效，对患者的生命体征和逆行性遗忘影响很小。
