Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.
J Magn Reson. 2019 Sep;306:192-194. doi: 10.1016/j.jmr.2019.07.040. Epub 2019 Jul 9.
Single types of methodologies are insufficient to adequately describe complex biological structures. As a result, integrated approaches that combine complementary data are being developed. Here, I describe the benefits of integrating solution and magic angle spinning BioNMR approaches to characterize structure and dynamics of protein assemblies.
单一类型的方法不足以充分描述复杂的生物结构。因此,正在开发结合互补数据的综合方法。在这里,我描述了整合溶液和魔角旋转 BioNMR 方法来表征蛋白质组装体的结构和动力学的好处。