Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei 10020, Taiwan.
Department of Pediatric Nephrology, Changhua Christian Children's Hospital, Changhua 50006, Taiwan.
Int J Environ Res Public Health. 2019 Jul 9;16(13):2436. doi: 10.3390/ijerph16132436.
The purpose of this study is to explore the association between proximity to open space and adult renal function. This was a cross-sectional study. Adult residents of Taipei metropolis were recruited in the analysis. The proximity of each subject to open space was measured using the Geographic Information System. Residents were divided into two groups: with and without chronic kidney disease (CKD). We made univariable comparisons between the two groups. The logistic regression models were used to estimate the odds ratio of CKD. Forest plot was used to examine the effect of interaction between distance to open space and subgroup variable on CKD. A total number of 21,656 subjects with mean age 53.6 years were enrolled in the study. Of the subjects, 2226 (10.28%) had CKD. The mean and standard deviation of distance to open space were 117.23 m and 80.19 m, respectively. Every 100 m distance to open space was associated with an odds ratio of 1.071 for CKD. Subgroup analysis revealed that residents of female, without hypertension, or without impaired fasting glucose (IFG) living more than 200 m from open spaces have greater odds of CKD than those living less than 200 m. Conclusions: Proximity to open space was associated with a lower prevalence of CKD among adults in Taiwan. Such association was enhanced among females and healthy adults without hypertension or impaired fasting glucose (IFG).
本研究旨在探讨接近开放空间与成人肾功能之间的关联。这是一项横断面研究。分析中招募了台北都会区的成年居民。使用地理信息系统测量每个研究对象接近开放空间的程度。将居民分为两组：有和没有慢性肾脏病（CKD）。我们对两组进行了单变量比较。使用逻辑回归模型估计 CKD 的优势比。森林图用于检查开放空间距离和亚组变量之间的交互作用对 CKD 的影响。共纳入 21656 名平均年龄为 53.6 岁的研究对象。其中 2226 名（10.28%）患有 CKD。开放空间距离的平均值和标准差分别为 117.23 米和 80.19 米。每增加 100 米到开放空间的距离，CKD 的优势比为 1.071。亚组分析显示，居住在距离开放空间超过 200 米的女性、没有高血压或没有空腹血糖受损（IFG）的成年人，其 CKD 的发病几率高于居住在 200 米以内的成年人。结论：在台湾，接近开放空间与成年人 CKD 的患病率较低有关。这种关联在女性和没有高血压或空腹血糖受损（IFG）的健康成年人中更为明显。
