San Diego State University, Department of Psychology, San Diego, CA, USA.
Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Addict Behav. 2019 Nov;98:106041. doi: 10.1016/j.addbeh.2019.106041. Epub 2019 Jul 2.
Thirdhand smoke (THS) residue lingers for months in homes of former smokers and may play a role in relapse after smoking cessation. This study examined the association between THS pollution as measured by the level of nicotine in house dust and continued abstinence from smoking.
Participants were 65 cigarette smokers who reported they were enrolled in any type of smoking cessation program, had set a specific date to quit, and had biochemical verification of continuous abstinence at 1-week (W1), 1-month (M1), 3-months (M3), or 6-months (M6) after their quit date. House dust samples collected at baseline before quitting were analyzed for nicotine concentration (μg/g) and nicotine loading (μg/m) using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Controlling for age, gender, overall and indoor smoking rates, and years lived in their home, dust nicotine concentration and loading predicted abstinence at W1, M1, M3, and M6. A 10-fold increase in dust nicotine loading and concentration were associated with approximately 50% lower odds of remaining abstinent.
Findings suggest nicotine in house dust may play a role in facilitating relapse after smoking cessation. Additional research is warranted to investigate the causal role of THS residue in homes of former smokers on cravings and continued abstinence.
三手烟（THS）残留物在曾经吸烟的家庭中会持续存在数月，并且可能在戒烟后复吸中发挥作用。本研究检测了通过房屋灰尘中尼古丁水平测量的 THS 污染与戒烟后持续不吸烟之间的关联。
参与者为 65 名香烟吸烟者，他们报告说他们参加了任何类型的戒烟计划，设定了具体的戒烟日期，并且在戒烟后 1 周（W1）、1 个月（M1）、3 个月（M3）或 6 个月（M6）时通过生物化学验证证明连续不吸烟。在戒烟前的基线阶段收集的房屋灰尘样本使用液相色谱-串联质谱法（LC-MS/MS）进行尼古丁浓度（μg/g）和尼古丁负荷（μg/m）的分析。
控制年龄、性别、总体和室内吸烟率以及在家中居住的年限，灰尘中的尼古丁浓度和负荷预测了 W1、M1、M3 和 M6 的戒烟情况。灰尘中尼古丁负荷和浓度增加 10 倍与持续戒烟的可能性降低约 50%相关。
研究结果表明，房屋灰尘中的尼古丁可能在戒烟后复吸中发挥作用。需要进一步研究以调查前吸烟者家中 THS 残留对烟瘾和持续戒烟的因果作用。
