New Drug Development Center (NDDC), Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), 80 Cheombok-ro, Dong-gu, Daegu 701-310, Korea.
Department of New Drug Discovery and Development, Chungnam National University, Daejon 305-764, Korea.
Molecules. 2019 Jul 19;24(14):2634. doi: 10.3390/molecules24142634.
Hypervalent iodine reagents are of considerable relevance in organic chemistry as they can provide a complementary reaction strategy to the use of traditional transition metal chemistry. Over the past two decades, there have been an increasing number of applications including stoichiometric oxidation and catalytic asymmetric variations. This review outlines the main advances in the past 10 years in regard to alkene heterofunctionalization chemistry using achiral and chiral hypervalent iodine reagents and catalysts.
高价碘试剂在有机化学中具有重要的应用价值，因为它们可以为传统过渡金属化学的应用提供一种补充的反应策略。在过去的二十年中，高价碘试剂在包括计量氧化和催化不对称变体等方面的应用越来越多。本文综述了过去 10 年中使用手性和非手性高价碘试剂和催化剂进行烯烃杂官能化化学的主要进展。
