碘(V)基氧化剂在氧化反应中的应用。

Iodine(V)-Based Oxidants in Oxidation Reactions.

机构信息

School of Chemical Sciences, Goa University, Taleigao Plateau 403206, Goa, India.

Chemistry Division, School of Advanced Sciences (SAS), Vellore Institute of Technology, Chennai 600127, Tamil Nadu, India.

出版信息

Molecules. 2023 Jul 6;28(13):5250. doi: 10.3390/molecules28135250.

DOI:10.3390/molecules28135250

PMID:37446912

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10343256/

Abstract

The chemistry of hypervalent iodine reagents has now become quite valuable due to the reactivity of these compounds under mild reaction conditions and their resemblance in chemical properties to transition metals. The environmentally friendly nature of these reagents makes them suitable for Green Chemistry. Reagents with a dual nature, such as iodine(III) reagents, are capable electrophiles, while iodine(V) reagents are known for their strong oxidant behavior. Various iodine(V) reagents including IBX and DMP have been used as oxidants in organic synthesis either in stoichiometric or in catalytic amounts. In this review article, we describe various oxidation reactions induced by iodine(V) reagents reported in the past decade.

摘要

由于这些化合物在温和的反应条件下具有反应活性，并且它们在化学性质上类似于过渡金属，因此高价碘试剂的化学性质变得非常有价值。这些试剂具有环保性质，因此适合绿色化学。具有双重性质的试剂，如三碘试剂，是亲电试剂，而五碘试剂则以强氧化剂行为而闻名。各种五碘试剂，包括 IBX 和 DMP，已被用作有机合成中的氧化剂，无论是在化学计量还是催化量下。在这篇综述文章中，我们描述了过去十年中报道的各种由五碘试剂引发的氧化反应。