Jeon You Hoon, Lee Yong Ju, Sohn Myung Hyun, Lee Hae Ran
Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Korea.
Allergy and Clinical Immunology Research Center, Hallym University College of Medicine, Hwaseong, Korea.
Allergy Asthma Immunol Res. 2019 Sep;11(5):655-663. doi: 10.4168/aair.2019.11.5.655.
To evaluate the effects of daily vacuuming of mattresses on the concentration of house dust mite (HDM) allergens and on allergic rhinitis (AR) symptoms in children sensitized to HDM.
Forty children between the ages of 6 and 12 years with mild persistent AR and sensitized only to HDM were enrolled and randomly allocated to 2 groups. Caregivers of children in the experimental group cleaned the children's rooms and vacuumed their mattresses daily for 2 weeks. Caregivers of children in the control group cleaned the children's rooms without vacuuming mattresses. Symptoms of AR were checked weekly and dust samples were collected from the mattresses before and after the study.
Demographics at the beginning of the study were not significantly different between the 2 groups. In the experimental group, symptoms of AR and dust weight were significantly decreased after 2 weeks (total symptoms of AR, <0.001; sneezing, < 0.001; rhinorrhea, <0.001; nasal obstruction, < 0.001; itching, <0.001; and dust weight, = 0.006). The concentrations of HDM allergens were not changed significantly (Der p1, = 0.333; Der f1, = 0.841). In the control group, there were no significant changes in symptoms of AR, dust weight, or the concentration of HDM allergens.
Our findings showed that daily vacuuming of mattresses reduced dust weight and symptoms of AR. However, the concentration of HDM allergens did not significantly decrease.
评估每日对床垫进行吸尘处理对屋尘螨（HDM）过敏原浓度以及对HDM致敏儿童过敏性鼻炎（AR）症状的影响。
招募40名年龄在6至12岁之间、患有轻度持续性AR且仅对HDM致敏的儿童，并将其随机分为2组。实验组儿童的照顾者每天清洁儿童房间并对床垫进行吸尘处理，持续2周。对照组儿童的照顾者清洁儿童房间但不对床垫进行吸尘。每周检查AR症状，并在研究前后从床垫上收集灰尘样本。
研究开始时两组的人口统计学特征无显著差异。在实验组中，2周后AR症状和灰尘重量显著降低（AR总症状，<0.001；打喷嚏，<0.001；流涕，<0.001；鼻塞，<0.001；瘙痒，<0.001；灰尘重量，=0.006）。HDM过敏原浓度无显著变化（Der p1，=0.333；Der f1，=0.841）。在对照组中，AR症状、灰尘重量或HDM过敏原浓度均无显著变化。
我们的研究结果表明，每日对床垫进行吸尘可降低灰尘重量和AR症状。然而，HDM过敏原浓度并未显著降低。
