Bahadori Effat, Farjami Zahra, Rezayi Majid, Lngari Hadis, Darroudi Majid, Avan Amir, Ghayour-Mobarhan Majid
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Diabetes Metab Syndr. 2019 Mar-Apr;13(2):1561-1568. doi: 10.1016/j.dsx.2019.03.002. Epub 2019 Mar 8.
Metabolic syndrome is a main clinical challenge of global health which is growing universally. It would be resulted from over-consumption of energy, increased obesity, and lack of movement during life. The metabolic syndrome causes a five-fold increase in the risk of type 2 diabetes mellitus and a double increase in the risk of rising cardiovascular disease over the next 5-10 years. Based on this, more attention has been drawn to the diagnosis and treatment options of this disease. Nanotechnology is one of the preferred methods for improving this disease. This way is a natural development in many health domains, including synthetic and nanostructures. The use of nanoparticles with the purpose of increase the effectiveness of treatment, decrease the side effects and the amount of drug usage, through their small size, permeability and maintenance strength lead to their absorption by target organs. Meanwhile, different nanoparticles with consumption values and particle size have been investigated.
代谢综合征是全球健康面临的主要临床挑战，且在全球范围内日益普遍。它是由能量摄入过多、肥胖加剧以及生活中缺乏运动导致的。代谢综合征会使2型糖尿病的发病风险增加五倍，并使未来5至10年心血管疾病发病风险翻倍。基于此，该疾病的诊断和治疗方案受到了更多关注。纳米技术是改善该疾病的首选方法之一。这种方式是包括合成和纳米结构在内的许多健康领域的自然发展。使用纳米颗粒旨在提高治疗效果、减少副作用和药物用量，因其尺寸小、渗透性强和维持强度高，可被靶器官吸收。与此同时，已对具有不同消耗值和粒径的各种纳米颗粒进行了研究。
