Girum Tadele, Shumbej Teha, Shewangizaw Misgun
1Department of Public health, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.
2Department of Medical laboratory science, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.
Trop Dis Travel Med Vaccines. 2019 Jul 12;5:11. doi: 10.1186/s40794-019-0090-z. eCollection 2019.
Globally malaria remains one of the high burden diseases particularly in developing countries. Ethiopia is one of the sub-Saharan countries highly endemic to malaria. Although, recently the burden of malaria was reduced remarkably through public health interventions designed during the Millennium Development Goals, it is still a major public health problem in Ethiopia. Hence, measuring the burden of the disease and assessing the trend is very important for monitoring the extent and changes over a period of time.
This study aimed to assess the burden of malaria in terms of death and Disability-Adjusted Life Years lost (DALY) between 2000 and 2016.
The research used data from Global Health Estimate 2016; that originally collected the information through vital registration, verbal autopsy, surveys, reports, published scientific articles, Global Burden of Disease study (GBD 2016) and modeling.
In 2016 there were an estimated 2,927,266 (95% CI, 525,000-6,983,000) new malaria cases in Ethiopia. It caused an estimated 4,782 deaths (95% CI 122.5-12,750) with a crude death rate of 4.7/100,000 and Age-standardized death rate (ASDR) of 4.9/100,000 population. However, the number of deaths due to malaria declined by 54% from the 2000's record of 10,412 deaths (95% CI 98.8-16180) within 16 years and ASDR declined by 63% from the 2000 record. In the same year, DALY due to malaria was 365,900 years (187,000 years among male and 178,900 years among females). It contributed for 0.78% of the total DALY in Ethiopia and 1% of the global DALY due to malaria. Around 332,100 life years (YLL) were lost and 35,200 years were lived with disability (YLD) due to malaria. Mortality and DALY related to malaria is slightly higher among males; and under 5 children are highly affected.
Although, the burden of malaria is remarkably declining in Ethiopia; with a higher level of mortality and DALY, it still remained one of the public health problems. Therefore, strengthening the existing malaria prevention program is important to eliminate the disease within the target period.
在全球范围内，疟疾仍然是高负担疾病之一，尤其是在发展中国家。埃塞俄比亚是撒哈拉以南疟疾高度流行的国家之一。尽管最近通过千年发展目标期间设计的公共卫生干预措施，疟疾负担显著降低，但在埃塞俄比亚它仍然是一个主要的公共卫生问题。因此，衡量该疾病的负担并评估其趋势对于监测一段时间内的程度和变化非常重要。
本研究旨在评估2000年至2016年期间疟疾在死亡和伤残调整生命年损失（DALY）方面的负担。
该研究使用了《2016年全球卫生估计》的数据；这些数据最初是通过生命登记、口头尸检、调查、报告、已发表的科学文章、全球疾病负担研究（GBD 2016）和建模收集的。
2016年，埃塞俄比亚估计有2,927,266例（95%可信区间，525,000 - 6,983,000）新疟疾病例。估计导致4,782人死亡（95%可信区间122.5 - 12,750），粗死亡率为4.7/10万，年龄标准化死亡率（ASDR）为4.9/10万人口。然而，疟疾导致的死亡人数在16年内比2000年记录的10,412人死亡（95%可信区间98.8 - 16,180）下降了54%，ASDR比2000年的记录下降了63%。同年，疟疾导致的DALY为365,900年（男性为187,000年，女性为178,900年）。它占埃塞俄比亚总DALY的0.78%，占全球疟疾DALY的1%。由于疟疾，约332,100个生命年（YLL）损失，35,200年带病生存（YLD）。与疟疾相关的死亡率和DALY在男性中略高；5岁以下儿童受影响严重。
尽管埃塞俄比亚的疟疾负担正在显著下降；但由于死亡率和DALY水平较高，它仍然是公共卫生问题之一。因此，加强现有的疟疾预防计划对于在目标时期内消除该疾病很重要。
