El-Tarabany Mahmoud S, Atta Mostafa A, Emara Sana S, Mostafa Mohamed M
Department of Animal Wealth Development, Faculty of Veterinary Medicine, Zagazig University, El-Zeraa Str. 114, Zagazig, Sharkia, 44511, Egypt.
Biological Applications Department, Radioisotopes Applications Division, NRC, Atomic Energy Authority, Inshas, Cairo, Egypt.
Trop Anim Health Prod. 2020 Jan;52(1):301-308. doi: 10.1007/s11250-019-02017-7. Epub 2019 Jul 23.
The aim was to explore the impact of periconceptional folic acid or flaxseed oil (FXO) supplementation on fertility, progesterone profile, and blood chemistry in pregnant ewes during the breeding season. In total, 54 Ossimi ewes were divided into three groups (18 animals each). The control treatment (CON) fed a basal diet only, while the others fed the basal diet and supplemented every other day with a single bolus of folic acid (FO 500 μg/head) or flaxseed oil (FX 50 ml/head). During the early stage of pregnancy, the FO and FX groups showed significantly higher serum antioxidant activity (glutathione and superoxide dismutase) as compared with the control CON group (P = 0.012 and 0.007, respectively). Although no significant variations were detected in the serum nitric oxide levels during the early stage and mid-stage of pregnancy, the FO and FX groups showed significantly lower serum nitric oxide concentration in the late stage of pregnancy (P = 0.001). The FO and FX groups showed significantly higher serum progesterone concentrations during the early stage (10.9 and 11.4 ng/ml, respectively) and mid-stage (22.2 and 23.4 ng/ml, respectively) of pregnancy as compared with the CON group (7.72 and 13.9 ng/ml, respectively). The FX group exhibited a significantly higher lambing rate (P = 0.034), as well as the proportion of female lambs (P = 0.029) as compared with the CON group. In conclusion, supplementing Ossimi ewes with folic acid or FXO significantly improved the progesterone profile during pregnancy. Moreover, the FXO supplementation significantly increased the lambing rate and the female lamb rate as compared with the control group.
本研究旨在探讨围孕期补充叶酸或亚麻籽油（FXO）对繁殖季节怀孕母羊生育力、孕酮水平及血液生化指标的影响。总共54只奥西米母羊被分为三组（每组18只）。对照组（CON）仅饲喂基础日粮，而其他两组在基础日粮的基础上每隔一天补充一次叶酸（500μg/头）或亚麻籽油（50ml/头）。在怀孕早期，叶酸组和亚麻籽油组的血清抗氧化活性（谷胱甘肽和超氧化物歧化酶）显著高于对照组（P分别为0.012和0.007）。虽然在怀孕早期和中期血清一氧化氮水平未检测到显著变化，但在怀孕后期，叶酸组和亚麻籽油组的血清一氧化氮浓度显著降低（P = 0.001）。与对照组相比，叶酸组和亚麻籽油组在怀孕早期（分别为10.9和11.4ng/ml）和中期（分别为22.2和23.4ng/ml）的血清孕酮浓度显著更高（对照组分别为7.72和13.9ng/ml）。与对照组相比，亚麻籽油组的产羔率（P = 0.034）以及母羊羔比例（P = 0.029）显著更高。总之，给奥西米母羊补充叶酸或FXO可显著改善孕期孕酮水平。此外，与对照组相比，补充FXO可显著提高产羔率和母羊羔率。
