NMIMS, School of Pharmacy & Technology Management, Shirpur (Maharashtra), India.
Department of Pharmacy, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, Bandarsindri, Ajmer, India.
Curr Pharm Des. 2019;25(9):937-945. doi: 10.2174/1381612825666190507115504.
The global market of pharmaceuticals has witnessed a new revolution recently in the form of threedimensional printing (3D) technology. 3D printing has its existence since the 1980s that uses a 3D printer to manufacture the different dosage forms through computer-aided drug design technology. The need for 3D printing is due to numerous advantages like personalized medicine, tailored doses, rapid disintegration in case of SLS technique, incorporation of high doses and taste masking capacity. The different techniques used in 3D printing are Powder based (PB), Semi-solid extrusion (EXT), Fused deposition modeling (FDM), Stereolithographic (SLA) and Selective laser sintering (SLS) 3D printing. However, from the latest reports of association of pharmaceutical 3D printing technology, it is evidenced that this technology is still in its infancy and its potential is yet to be fully explored. The present review includes sections for introduction and scope of 3D printing, personalized medicines and their approaches, historical aspects, research milestones, and various 3D printing techniques.
最近，药品的全球市场出现了一场新的革命，这就是三维打印（3D）技术。3D 打印技术自 20 世纪 80 年代以来就已经存在，它使用 3D 打印机通过计算机辅助药物设计技术来制造不同的剂型。对 3D 打印技术的需求源于许多优势，如个性化药物、定制剂量、在 SLS 技术下快速崩解、高剂量的结合和掩味能力。3D 打印中使用的不同技术有粉末基础（PB）、半固态挤压（EXT）、熔融沉积建模（FDM）、立体光刻（SLA）和选择性激光烧结（SLS）3D 打印。然而，从药品 3D 打印技术协会的最新报告来看，这项技术仍处于起步阶段，其潜力尚未得到充分挖掘。本综述包括 3D 打印的引言和范围、个性化药物及其方法、历史方面、研究里程碑和各种 3D 打印技术等部分。
