K L College of Pharmacy, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Andhra Pradesh, India.
Department of Pharmacy, NRK & KSR Gupta College of Pharmacy, Tenali, Guntur, Andhra Pradesh, India.
Curr Drug Targets. 2021;22(16):1901-1914. doi: 10.2174/1389450122666210120142416.
Three Dimensional (3D) printing is a promising method for quick prototyping and manufacturing of any material. It is similar to photocopy or printing, where the new materials are formed on layers (3D) like their mother component. Following its growth and advancement in the 1980s, its application in pharmaceuticals is still limited. It has become one of the most innovative and influential tools serving as a technology for developing dosage forms from the last decade. The potential of 3D printing to produce drugs for precise measurement customized to specific patients' needs has shown the possibility of developing personalized medicines to novel dosage forms. The breakthrough allows the clear perception of the dosage structures on different shapes, sizes, surfaces and the associated challenges in delivering them by using such designed conditions. There are different difficulties related to the correct utilization of 3D imprinting in the pharmaceuticals, which have a strong impact on the scope of this technology. Recent advancements in the field of 3D printing technology used in the pharmaceutical industry mainly focused on different techniques for the fabrication of different dosage forms. The Food and Drug Administration's (FDA) recent approval of the first 3D prescription highlights possibilities for 3D printing innovation in the field of pharmaceutical drug supply. This analysis assesses 3D printing advancement possibilities, particularly in the area of custom prescriptions. This technology can be regarded as the future produced on demand, low-cost solid dosage forms and helps minimize side effects due to overdose.
三维（3D）打印是一种快速原型制作和任何材料制造的有前途的方法。它类似于影印或打印，新的材料在层（3D）中形成，就像它们的母组件一样。在 20 世纪 80 年代的发展和进步之后，它在制药方面的应用仍然有限。它已成为最具创新性和影响力的工具之一，作为过去十年中开发剂型的技术。3D 打印能够生产精确测量的药物，以满足特定患者的需求，为开发个性化药物提供了新的剂型。这一突破使人们能够清楚地了解不同形状、大小、表面的剂量结构，以及通过使用这种设计条件来输送它们所带来的挑战。在制药中正确使用 3D 压印存在不同的困难，这对该技术的范围有很大的影响。最近在制药行业 3D 打印技术领域的进展主要集中在不同技术用于制造不同的剂型上。食品和药物管理局（FDA）最近批准了第一个 3D 处方，这突显了 3D 打印在制药供应领域创新的可能性。本分析评估了 3D 打印的发展可能性，特别是在定制处方领域。这项技术可以被视为按需生产的未来，低成本的固体剂型，并有助于最大限度地减少因过量服用而产生的副作用。
