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在芬兰赫尔辛基,从 1996 年到 2016 年的 20 年间,哮喘患病率的增长趋于平稳,成年人的症状也有所减轻。

The increase of asthma prevalence has levelled off and symptoms decreased in adults during 20 years from 1996 to 2016 in Helsinki, Finland.

机构信息

University of Helsinki, Helsinki, Finland.

Espoo City Health Services, Espoo, Finland.

出版信息

Respir Med. 2019 Aug;155:121-126. doi: 10.1016/j.rmed.2019.07.014. Epub 2019 Jul 19.

Abstract

BACKGROUND

Mortality and hospitalization due to asthma have decreased in many European countries, but asthma symptoms still cause a lot of morbidity and costs.

OBJECTIVES

We evaluated prevalence trends of asthma, asthma symptoms and allergic rhinoconjunctivitis in adults aged 20-69 years during a 20-year period from 1996 to 2016 in the city of Helsinki, the capital of Finland.

METHODS

Three cross-sectional postal surveys were conducted in random population samples 10 years apart. In 1996, 2006 and 2016, a total of 6062 (response rate 75.9%), 2449 (61.9%) and 4026 subjects (50.3%) took part, respectively.

RESULTS

In all responders, the prevalence of physician-diagnosed asthma was 6.6% in 1996, 10% in 2006 and 10.9% in 2016. The prevalence increased from 1996 to 2006, but stabilized from 2006 to 2016, both in men and women and in smokers and non-smokers. The prevalence of current asthma (8.5% in 2006 and 8.8% in 2016) and of asthma with rhinoconjunctivitis (7.6% in 2006 and 7.5% in 2016) remained also at the same level. Allergic rhinoconjunctivitis decreased significantly from 2006 (42.7%) to 2016 (39.0%, p = 0.004). Those with physician diagnosed asthma reported significantly less symptoms in 2016 compared to 2006 and 1996, although there was no change in smoking habits or medication use. Young asthmatics (20-29 years) without rhinoconjunctivitis reported least symptoms.

CONCLUSION

Previously observed increase of physician-diagnosed asthma prevalence in adults seems to be levelling off in Helsinki, and patients have fewer symptoms than 20 years ago. In addition, allergic rhinoconjunctivitis is less frequent than 10 years earlier. (247 words).

摘要

背景

在许多欧洲国家,哮喘导致的死亡率和住院率已经有所下降,但哮喘症状仍导致大量发病和医疗费用。

目的

我们评估了芬兰首都赫尔辛基 20 岁至 69 岁成年人在 1996 年至 2016 年的 20 年期间哮喘、哮喘症状和过敏性鼻结膜炎的流行趋势。

方法

我们每 10 年进行一次三阶段的横断面邮政调查,在 1996 年、2006 年和 2016 年,总共 6062(应答率为 75.9%)、2449(61.9%)和 4026 名(50.3%)参与者参与了调查。

结果

在所有应答者中,1996 年、2006 年和 2016 年,医生诊断的哮喘患病率分别为 6.6%、10%和 10.9%。1996 年至 2006 年,男性和女性、吸烟者和非吸烟者的哮喘患病率均有所增加,但自 2006 年以来已趋于稳定。目前哮喘(2006 年为 8.5%,2016 年为 8.8%)和哮喘合并鼻结膜炎(2006 年为 7.6%,2016 年为 7.5%)的患病率也保持在同一水平。过敏性鼻结膜炎从 2006 年(42.7%)显著下降至 2016 年(39.0%,p=0.004)。与 2006 年和 1996 年相比,2016 年被诊断患有哮喘的患者报告的症状明显减少,尽管吸烟习惯或用药情况没有变化。无鼻结膜炎的年轻哮喘患者(20-29 岁)报告的症状最少。

结论

在赫尔辛基,成年人中观察到的医生诊断哮喘患病率的增加似乎已趋于平稳,并且患者的症状比 20 年前有所减少。此外,过敏性鼻结膜炎的发病率比 10 年前要低。(247 个单词)

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