Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Department of Prevention and Sports Medicine, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany.
Res Sports Med. 2020 Apr-Jun;28(2):241-255. doi: 10.1080/15438627.2019.1647205. Epub 2019 Jul 25.
Regular moderate physical activity (PA) has been linked to beneficial adaptations in various somatic diseases (e.g. cancer, endocrinological disorders) and a reduction in all-cause mortality from several cardiovascular and neuropsychiatric diseases. This study was designed to investigate acute and prolonged exercise-induced cardio- and neurophysiological responses in endurance runners competing in the Munich Marathon. ReCaP (Running effects on Cognition and Plasticity) is a multimodal and longitudinal experimental study. This study included 100 participants (20-60 years). Six laboratory visits were included during the 3-month period before and the 3-month period after the Munich marathon. The multimodal assessment included laboratory measurements, cardiac and cranial imaging (MRI scans, ultrasound/echocardiography) and neurophysiological methods (EEG and TMS/tDCS), and vessel-analysis (e.g. retinal vessels and wave-reflection analyses) and neurocognitive measurements. The ReCaP study was designed to examine novel exercise-induced cardio- and neurophysiological responses to marathon running at the behavioral, functional and morphological levels. This study will expand our understanding of exercise-induced adaptations and will lead to more individually tailored therapeutic options.
定期进行适度的身体活动（PA）已被证明与各种躯体疾病（如癌症、内分泌紊乱）的有益适应有关，并降低了多种心血管和神经精神疾病的全因死亡率。本研究旨在调查参加慕尼黑马拉松的耐力跑者在急性和长期运动诱导的心肺和神经生理反应。ReCaP（跑步对认知和可塑性的影响）是一项多模态和纵向的实验研究。这项研究包括 100 名参与者（20-60 岁）。在慕尼黑马拉松比赛前的 3 个月和比赛后的 3 个月期间，共进行了 6 次实验室访问。多模态评估包括实验室测量、心脏和头部成像（MRI 扫描、超声/超声心动图）和神经生理学方法（EEG 和 TMS/tDCS），以及血管分析（如视网膜血管和波反射分析）和神经认知测量。ReCaP 研究旨在从行为、功能和形态学水平上研究马拉松跑对心肺和神经生理的新的运动诱导反应。本研究将扩展我们对运动诱导适应的理解，并为更个体化的治疗选择提供依据。
