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胰腺癌中的寡转移（肝寡转移胰腺癌的同期切除术：在回顾性多中心分析中对安全胰腺手术时代的一项原则提出质疑）

Oligometastases in pancreatic cancer (Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis).

作者信息

Voss Nina, Izbicki Jakob R, Nentwich Michael F

机构信息

Department of General, Visceral and Thoracic Surgery University Medical Center Hamburg-Eppendorf Hamburg Germany.

出版信息

Ann Gastroenterol Surg. 2019 Apr 29;3(4):373-377. doi: 10.1002/ags3.12255. eCollection 2019 Jul.

DOI:10.1002/ags3.12255
PMID:31346576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635688/
Abstract

The aim of the present review was to analyze the current data on surgery of synchronous liver metastases in pancreatic ductal adenocarcinoma (PDAC) in curative intent. A review of the literature was carried out to identify the current international concepts regarding surgery of liver metastases of PDAC and, furthermore, we addressed the current challenges of resection of liver metastases of PDAC. Resection of liver metastases in PDAC may provide survival benefit without compromising safety and quality of life in a highly selected group of patients.

摘要

本综述的目的是分析目前关于胰腺导管腺癌（PDAC）同步肝转移癌根治性手术的现有数据。我们进行了文献综述，以确定目前关于PDAC肝转移癌手术的国际理念，此外，我们还探讨了PDAC肝转移癌切除目前面临的挑战。对高度选择的一组患者而言，PDAC肝转移癌切除术可能在不影响安全性和生活质量的情况下带来生存益处。

相似文献

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Oligometastases in pancreatic cancer (Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis).胰腺癌中的寡转移（肝寡转移胰腺癌的同期切除术：在回顾性多中心分析中对安全胰腺手术时代的一项原则提出质疑）
Ann Gastroenterol Surg. 2019 Apr 29;3(4):373-377. doi: 10.1002/ags3.12255. eCollection 2019 Jul.
2
Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis.肝寡转移胰腺癌的同期切除术：在回顾性多中心分析中对安全胰腺手术时代一项原则的质疑
Surgery. 2016 Jul;160(1):136-144. doi: 10.1016/j.surg.2016.02.019. Epub 2016 Apr 3.
3
Patients with hepatic oligometastatic pancreatic body/tail ductal adenocarcinoma may benefit from synchronous resection.肝寡转移型胰体尾部导管腺癌患者可能从同步切除中获益。
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Cancers (Basel). 2019 Aug 1;11(8):1095. doi: 10.3390/cancers11081095.
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Simultaneous resection of the primary tumour and liver metastases after conversion chemotherapy versus standard therapy in pancreatic cancer with liver oligometastasis: protocol of a multicentre, prospective, randomised phase III control trial (CSPAC-1).胰腺癌伴肝脏寡转移患者经转化化疗后同期切除原发灶和肝转移灶与标准治疗的对比：一项多中心、前瞻性、随机对照 III 期临床试验（CSPAC-1）方案。
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本文引用的文献

1
FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer.FOLFIRINOX 或吉西他滨作为胰腺癌的辅助治疗。
N Engl J Med. 2018 Dec 20;379(25):2395-2406. doi: 10.1056/NEJMoa1809775.
2
Pancreatic, periampullary and biliary cancer with liver metastases: Should we consider resection in selected cases?伴有肝转移的胰腺癌、壶腹周围癌和胆管癌：在某些特定病例中我们是否应考虑手术切除？
World J Gastrointest Oncol. 2018 Aug 15;10(8):211-220. doi: 10.4251/wjgo.v10.i8.211.
3
[Oligometastasis in pancreatic cancer : Current state of knowledge and spectrum of local therapy].[胰腺癌寡转移：当前知识现状与局部治疗范围]
Chirurg. 2018 Jul;89(7):510-515. doi: 10.1007/s00104-018-0626-1.
4
Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology.《胰腺导管腺癌临床实践指南（2017 年第 2 版）》，NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2017 Aug;15(8):1028-1061. doi: 10.6004/jnccn.2017.0131.
5
Downstaging in Stage IV Pancreatic Cancer: A New Population Eligible for Surgery?IV 期胰腺癌降期：一个新的适合手术的人群？
Ann Surg Oncol. 2017 Aug;24(8):2397-2403. doi: 10.1245/s10434-017-5885-4. Epub 2017 May 17.
6
Cancer Statistics, 2017.《2017 年癌症统计》
CA Cancer J Clin. 2017 Jan;67(1):7-30. doi: 10.3322/caac.21387. Epub 2017 Jan 5.
7
Radical surgery of oligometastatic pancreatic cancer.寡转移胰腺癌的根治性手术
Eur J Surg Oncol. 2017 Feb;43(2):358-363. doi: 10.1016/j.ejso.2016.10.023. Epub 2016 Nov 9.
8
Is there a role for surgical resection in patients with pancreatic cancer with liver metastases responding to chemotherapy?对于化疗有反应的伴有肝转移的胰腺癌患者，手术切除是否能发挥作用？
Eur J Surg Oncol. 2016 Oct;42(10):1533-9. doi: 10.1016/j.ejso.2016.06.398. Epub 2016 Jun 29.
9
Synchronous resections of hepatic oligometastatic pancreatic cancer: Disputing a principle in a time of safe pancreatic operations in a retrospective multicenter analysis.肝寡转移胰腺癌的同期切除术：在回顾性多中心分析中对安全胰腺手术时代一项原则的质疑
Surgery. 2016 Jul;160(1):136-144. doi: 10.1016/j.surg.2016.02.019. Epub 2016 Apr 3.
10
Nationwide In-hospital Mortality Following Pancreatic Surgery in Germany is Higher than Anticipated.德国胰腺手术后的全国住院死亡率高于预期。
Ann Surg. 2016 Dec;264(6):1082-1090. doi: 10.1097/SLA.0000000000001693.