• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

中风患者管饲法的比较：鼻胃管饲法与口食管管饲法——一项初步研究。

Comparison of tube feeding in stroke patients: Nasogastric tube feeding versus oroesophageal tube feeding-A pilot study.

作者信息

Park Jung Wook, Park Ki Deok, Kim Tae Hee, Lee Jin Young, Lim Oh Kyung, Lee Ju Kang, Choi Cheol

机构信息

Department of Rehabilitation Medicine, Gachon University Gil Medical Center.

Department of Rehabilitation Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon.

出版信息

Medicine (Baltimore). 2019 Jul;98(30):e16472. doi: 10.1097/MD.0000000000016472.

DOI:10.1097/MD.0000000000016472
PMID:31348251
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6708800/
Abstract

BACKGROUNDS

Patients with central nervous system injuries present with dysphagia and may require non-oral feeding methods, like percutaneous endoscopic gastrostomy, nasogastric (NG) tube, or oroesophageal (OE) tube. The prevalence of pneumonia in patients with gastroesophageal reflux (GER) is significantly higher than that in patients without GER. We aimed to determine the most appropriate tube feeding with low risk of GER by comparing the results of 24-hour pH monitoring studies in patients who were administered 2 types of feeding: NG tube and OE tube.

METHODS

In this pilot study, 6 stroke patients underwent 24-hour esophageal pH monitoring during NG tube feeding and OE tube feeding, sequentially. Parameters collected included acid exposure time, mean esophageal pH, number of reflux episode, time of bolus reflux for both total 24-hour pH study data and postprandial data, and deMeester composite score.

RESULTS

Total acid reflux time (minutes) decreased more with OE tube feeding than that with NG tube feeding in the total 24-hour pH study. The number of reflux episodes decreased in both total and postprandial data with OE tube feeding versus NG tube feeding (P < .05). There were no significant differences in mean esophageal pH and total time of bolus reflux between the 2 groups.

CONCLUSIONS

Although we could not definitively conclude that OE tube feeding decreased the severity of GER compared with NG tube feeding, there were significant differences in 4 out of 9 parameters. OE tube can be a substitute for NG tube in patients with dysphagia after stroke leading to GER disease.

摘要

背景

中枢神经系统损伤患者存在吞咽困难，可能需要非经口喂养方法，如经皮内镜下胃造口术、鼻胃管或食管造口管。胃食管反流（GER）患者的肺炎患病率显著高于无GER的患者。我们旨在通过比较接受两种喂养方式（鼻胃管和食管造口管）的患者24小时pH监测研究结果，确定GER风险较低的最合适的管饲方式。

方法

在这项前瞻性研究中，6名中风患者在鼻胃管喂养和食管造口管喂养期间依次进行24小时食管pH监测。收集的参数包括酸暴露时间、平均食管pH值、反流发作次数、24小时pH研究数据和餐后数据的推注反流时间以及DeMeester综合评分。

结果

在24小时pH研究中，食管造口管喂养的总酸反流时间（分钟）比鼻胃管喂养减少得更多。与鼻胃管喂养相比，食管造口管喂养的总数据和餐后数据中的反流发作次数均减少（P<0.05）。两组之间的平均食管pH值和推注反流总时间无显著差异。

结论

虽然我们不能明确得出食管造口管喂养与鼻胃管喂养相比降低了GER严重程度的结论，但在9项参数中有4项存在显著差异。食管造口管可作为中风后吞咽困难导致GER疾病患者鼻胃管的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/686515053765/medi-98-e16472-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/020f3ed51a30/medi-98-e16472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/8264ce22cc80/medi-98-e16472-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/90dddfe10095/medi-98-e16472-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/168d611d4cd8/medi-98-e16472-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/e0707886bff5/medi-98-e16472-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/686515053765/medi-98-e16472-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/020f3ed51a30/medi-98-e16472-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/8264ce22cc80/medi-98-e16472-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/90dddfe10095/medi-98-e16472-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/168d611d4cd8/medi-98-e16472-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/e0707886bff5/medi-98-e16472-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6faf/6708800/686515053765/medi-98-e16472-g009.jpg

相似文献

1
Comparison of tube feeding in stroke patients: Nasogastric tube feeding versus oroesophageal tube feeding-A pilot study.中风患者管饲法的比较：鼻胃管饲法与口食管管饲法——一项初步研究。
Medicine (Baltimore). 2019 Jul;98(30):e16472. doi: 10.1097/MD.0000000000016472.
2
Gastroesophageal reflux during enteral feeding in stroke patients: a 24-hour esophageal pH-monitoring study.脑卒中患者肠内喂养期间的胃食管反流：24 小时食管 pH 监测研究。
J Stroke Cerebrovasc Dis. 2013 Apr;22(3):185-9. doi: 10.1016/j.jstrokecerebrovasdis.2011.07.008.
3
Changes in gastroesophageal reflux in patients with nasogastric tube followed by percutaneous endoscopic gastrostomy.经鼻胃管置管后行经皮内镜胃造瘘术患者胃食管反流的变化。
J Formos Med Assoc. 2011 Feb;110(2):115-9. doi: 10.1016/S0929-6646(11)60018-1.
4
The therapeutic effect and complications of oro-esophageal tube training in stroke patients.经口-食管管饲训练对脑卒中患者的治疗效果及并发症。
Clin Interv Aging. 2019 Jul 11;14:1255-1264. doi: 10.2147/CIA.S204835. eCollection 2019.
5
Effect of different tube feeding methods on gastroesophageal reflux features in preterm infants: a pH-impedance monitoring study.不同管饲方式对早产儿胃食管反流特征的影响：一项 pH 阻抗监测研究。
Eur J Pediatr. 2024 Nov;183(11):4755-4762. doi: 10.1007/s00431-024-05737-7. Epub 2024 Aug 30.
6
Nasogastric Feeding Tubes May Not Contribute to Gastroesophageal Reflux in Preterm Infants.经鼻胃管喂养不一定会导致早产儿胃食管反流。
Am J Perinatol. 2018 Jun;35(7):643-647. doi: 10.1055/s-0037-1608875. Epub 2017 Nov 30.
7
Twenty-four-hour esophageal impedance-pH monitoring in healthy preterm neonates: rate and characteristics of acid, weakly acidic, and weakly alkaline gastroesophageal reflux.健康早产儿24小时食管阻抗-pH监测：酸、弱酸性和弱碱性胃食管反流的发生率及特征
Pediatrics. 2006 Aug;118(2):e299-308. doi: 10.1542/peds.2005-3140. Epub 2006 Jul 10.
8
[Effect of sarpogrelate in enteral feeding of patients with gastroesophageal reflux (GER)].沙格雷酯对胃食管反流（GER）患者肠内营养的影响
Nihon Ronen Igakkai Zasshi. 2006 Jul;43(4):492-7. doi: 10.3143/geriatrics.43.492.
9
Nasogastric intubation causes gastroesophageal reflux in patients undergoing elective laparotomy.鼻胃管插管会导致择期剖腹手术患者发生胃食管反流。
Surgery. 2001 Nov;130(5):788-91. doi: 10.1067/msy.2001.116029.
10
Fundoplication and gastrostomy versus image-guided gastrojejunal tube for enteral feeding in neurologically impaired children with gastroesophageal reflux.胃底折叠术与胃造口术对比影像引导下胃空肠管用于神经功能受损的胃食管反流儿童的肠内喂养
J Pediatr Surg. 2002 Mar;37(3):407-12. doi: 10.1053/jpsu.2002.30849.

引用本文的文献

1
Naso-intestinal versus gastric tube for enteral nutrition in patients undergoing mechanical ventilation: a systematic review and meta-analysis.机械通气患者肠内营养使用鼻肠管与胃管的比较：一项系统评价和荟萃分析
Syst Rev. 2025 Jan 14;14(1):13. doi: 10.1186/s13643-024-02743-6.
2
Association between gastroesophageal reflux disease and stroke: a bidirectional Mendelian randomization study.胃食管反流病与中风之间的关联：一项双向孟德尔随机化研究。
Front Neurol. 2024 Jan 23;14:1295051. doi: 10.3389/fneur.2023.1295051. eCollection 2023.
3
[Preparation and Performance Evaluation of Polyacrylamide Hydrogel Coating on the Surface of Silicone Rubber Nasogastric Tube].

本文引用的文献

1
Oropharyngeal pH monitoring for laryngopharyngeal reflux: is it a reliable test before therapy?咽喉反流的咽喉部 pH 监测：治疗前该检查是否可靠？
J Voice. 2013 Jan;27(1):84-9. doi: 10.1016/j.jvoice.2012.08.006. Epub 2012 Nov 15.
2
Percutaneous Endoscopic Gastrostomy Prevents Gastroesophageal Reflux in Patients with Nasogastric Tube Feeding: A Prospective Study with 24-Hour pH Monitoring.经皮内镜下胃造口术预防鼻胃管喂养患者胃食管反流：一项 24 小时 pH 监测的前瞻性研究。
Gut Liver. 2011 Sep;5(3):288-92. doi: 10.5009/gnl.2011.5.3.288. Epub 2011 Aug 18.
3
A new technique for measurement of pharyngeal pH: normal values and discriminating pH threshold.
[硅橡胶鼻胃管表面聚丙烯酰胺水凝胶涂层的制备及性能评价]
Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Jul;54(4):782-787. doi: 10.12182/20230760205.
4
Bibliometric analysis of global research trends on post-stroke pneumonia: Current development status and research Frontiers.基于文献计量学的全球卒中后肺炎研究趋势分析：现状与研究前沿。
Front Public Health. 2022 Aug 2;10:950859. doi: 10.3389/fpubh.2022.950859. eCollection 2022.
一种测量咽部pH值的新技术：正常值及鉴别pH阈值
J Gastrointest Surg. 2009 Aug;13(8):1422-9. doi: 10.1007/s11605-009-0915-6. Epub 2009 May 7.
4
Intermittent oro-esophageal tube feeding in acute stroke patients -- a pilot study.急性中风患者间歇性经口-食管管饲——一项试点研究。
Acta Neurol Scand. 2006 Jan;113(1):36-9. doi: 10.1111/j.1600-0404.2005.00534.x.
5
Prevalence of gastroesophageal reflux in patients who develop pneumonia following percutaneous endoscopic gastrostomy: a 24-hour pH monitoring study.
Dysphagia. 1996 Spring;11(2):87-9. doi: 10.1007/BF00417895.
6
Oro-esophageal tube feeding: an alternative to nasogastric or gastrostomy tubes.口-食管管饲：鼻胃管或胃造瘘管的替代方法。
Dysphagia. 1988;2(4):220-1. doi: 10.1007/BF02414430.
7
Timing of videofluoroscopic, manometric events, and bolus transit during the oral and pharyngeal phases of swallowing.吞咽口腔期和咽期过程中电视荧光吞咽造影、测压事件及食团通过的时间。
Dysphagia. 1989;4(1):8-15. doi: 10.1007/BF02407397.