Yu Feng, Xin Mengxue, Liu Nan, Huang Na, Lu Jianhui
The First Affiliated Hospital of GuangZhou University of Chinese Medicine.
Guangzhou University of Chinese Medicine, Guangzhou, China.
Medicine (Baltimore). 2019 Jul;98(30):e16633. doi: 10.1097/MD.0000000000016633.
Chronic obstructive pulmonary disease (COPD) is a chronic and progressive disease that represents an important public health challenge nowadays. Despite the growing number of studies assessing the rehabilitation outcome of Wuqinxi for COPD, their many variables and observations are often explored with a relatively small sample size, accordingly maybe lead to potential false-positive results. The aim of this systematic review and meta-analysis is to evaluate the rehabilitation efficacy of Wuqinxi for COPD.
A detailed search for articles up to June 2019 will be performed to identify randomized controlled trials for Wuqinxi in COPD. The following database will be used: PUBMED, Embase, Scopus, Web of Science, Google Scholar, Cochrane Library, Sino Med, Chinese National Knowledge Infrastructure, Chinese Science and Technology Periodicals Database, and Wanfang Database. Grey literature will be explored and the selection of studies, data extraction and validation will performed independently by 2 reviewers using predefined selection criteria and quality indicators. Stata V.13.0 and Review manager 5.3 software will be used for data synthesis, sensitivity analysis, subgroup analysis, and risk of bias assessment. We will use the grading of recommendations assessment, development, and evaluation system to assess the quality of evidence.
This research will update previous evidence summaries and provide a quantitative and standardized assessment of the rehabilitation efficacy of Wuqinxi for COPD.
This systematic review will generate the latest evidence for determining whether Wuqinxi has a positive rehabilitation effect for COPD.PROSPERO registration number: PROSPERO CRD 42019120960.
慢性阻塞性肺疾病（COPD）是一种慢性进行性疾病，是当今一项重大的公共卫生挑战。尽管评估五禽戏对COPD康复效果的研究越来越多，但由于样本量相对较小，往往对众多变量和观察指标进行探索，可能导致潜在的假阳性结果。本系统评价和荟萃分析的目的是评估五禽戏对COPD的康复疗效。
将详细检索截至2019年6月的文章，以确定关于五禽戏治疗COPD的随机对照试验。将使用以下数据库：PUBMED、Embase、Scopus、Web of Science、谷歌学术、Cochrane图书馆、中国生物医学文献数据库、中国知网、维普数据库和万方数据库。将探索灰色文献，由2名审阅者使用预先定义的选择标准和质量指标独立进行研究选择、数据提取和验证。将使用Stata V.13.0和Review manager 5.3软件进行数据合成、敏感性分析、亚组分析和偏倚风险评估。我们将使用推荐分级评估、制定和评价系统来评估证据质量。
本研究将更新以往的证据总结，并对五禽戏对COPD的康复疗效进行定量和标准化评估。
本系统评价将为确定五禽戏对COPD是否具有积极的康复效果提供最新证据。国际前瞻性系统评价注册编号：PROSPERO CRD 42019120960。
