单剂量头孢噻肟肌内注射可治愈新生儿淋菌性眼炎。
Single-dose cefotaxime intramuscularly cures gonococcal ophthalmia neonatorum.
作者信息
Lepage P, Bogaerts J, Kestelyn P, Meheus A
机构信息
Department of Paediatrics, Kigali Hospital, Rwanda.
出版信息
Br J Ophthalmol. 1988 Jul;72(7):518-20. doi: 10.1136/bjo.72.7.518.
Abstract
Nine neonates with culture proved gonococcal ophthalmia neonatorum were treated with a single intramuscular injection of 100 mg/kg of cefotaxime without topical antibiotic therapy. Five of the nine strains were penicillinase-producing Neisseria gonorrhoeae. All nine cases were clinically and microbiologically cured, and no side effects were observed.
摘要
9例经培养证实为淋菌性新生儿眼炎的新生儿接受了单次肌内注射100mg/kg头孢噻肟治疗，未进行局部抗生素治疗。9株菌株中有5株为产青霉素酶的淋病奈瑟菌。所有9例在临床和微生物学上均治愈，且未观察到副作用。
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