Department of Biomedical Sciences, Seoul National University College of Medicine.
Department of Internal Medicine, Armed Forces Capital Hospital.
Curr Opin Nephrol Hypertens. 2019 Nov;28(6):552-559. doi: 10.1097/MNH.0000000000000536.
Acute kidney injury (AKI) is a critical condition associated with poor patient outcomes. We aimed to review the current concepts and future strategies regarding AKI risk prediction models.
Recent studies have shown that AKI occurs frequently in patients with common risk factors and certain medical conditions. Prediction models for AKI risk have been reported in medical fields such as critical care medicine, surgery, nephrotoxic agent exposure, and others. However, practical, generalizable, externally validated, and robust AKI prediction models remain relatively rare. Further efforts to develop AKI prediction models based on comprehensive clinical data, artificial intelligence, improved delivery of care, and novel biomarkers may help improve patient outcomes through precise AKI risk prediction.
This brief review provides insights for current concepts for AKI prediction model development. In addition, by overviewing the recent AKI prediction models in various medical fields, future strategies to construct advanced AKI prediction models are suggested.
急性肾损伤(AKI)是一种与患者预后不良相关的危急情况。本综述旨在回顾 AKI 风险预测模型的最新概念和未来策略。
最近的研究表明,AKI 在具有常见危险因素和某些医疗条件的患者中经常发生。AKI 风险预测模型已在重症医学、外科、肾毒性药物暴露等医学领域中得到报道。然而,实用、可推广、外部验证和稳健的 AKI 预测模型仍然相对较少。进一步努力基于全面的临床数据、人工智能、改进的护理提供和新型生物标志物开发 AKI 预测模型,可能有助于通过精确的 AKI 风险预测改善患者预后。
本简要综述为 AKI 预测模型开发的当前概念提供了深入了解。此外,通过综述各种医学领域的最近 AKI 预测模型,提出了构建先进 AKI 预测模型的未来策略。