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当前促进营养与癌症预防研究的机会——跨学科视角。

Current opportunities to catalyze research in nutrition and cancer prevention - an interdisciplinary perspective.

出版信息

BMC Med. 2019 Jul 30;17(1):148. doi: 10.1186/s12916-019-1383-9.

Abstract

Cancer Research UK and Ludwig Cancer Research convened an inaugural international Cancer Prevention and Nutrition Conference in London on December 3-4, 2018. Much of the discussion focused on the need for systematic, interdisciplinary approaches to better understand the relationships of nutrition, exercise, obesity and metabolic dysfunction with cancer development. Scientists at the meeting underscored the importance of studying the temporal natural history of exposures that may cumulatively impact cancer risk later in life.A robust dialogue identified obesity as a major risk for cancer, and the food environment, especially high energy and low nutrient processed foods, as strong and prevalent risk factors for obesity. Further engagement highlighted challenges in the post-diagnostic setting, where similar opportunities to understand the complex interplay of nutrition, physical activity, and weight will inform better health outcomes.Going forward, holistic research approaches, encompassing insights from multiple disciplines and perspectives, will catalyze progress urgently needed to prevent cancer and improve public health.

摘要

英国癌症研究中心和路德维希癌症研究所在 2018 年 12 月 3 日至 4 日在伦敦召开了首届国际癌症预防与营养会议。会议的大部分讨论集中在需要系统地采用跨学科方法,以更好地了解营养、运动、肥胖和代谢功能障碍与癌症发展之间的关系。与会科学家强调了研究可能会累积影响以后生活中癌症风险的暴露的时间自然史的重要性。强有力的对话确定了肥胖是癌症的主要风险因素,而食物环境,特别是高能量、低营养的加工食品,是肥胖的强烈和普遍的风险因素。进一步的讨论强调了在诊断后环境中所面临的挑战,在这种环境中,有机会了解营养、身体活动和体重之间的复杂相互作用,将为改善健康结果提供信息。展望未来,综合研究方法,包括来自多个学科和视角的见解,将推动迫切需要预防癌症和改善公众健康的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db47/6664739/f246d7014364/12916_2019_1383_Fig1_HTML.jpg

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