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哮喘发作后持续低氧血症。

Persistent hypoxemia after an asthma attack.

作者信息

Deana Cristian, Conangla Laura, Vetrugno Luigi, Saltarini Massimiliano, Buttera Stefania, Bove Tiziana, Bassi Flavio, De Monte Amato

机构信息

Anesthesiology and Intensive Care 1, Department of Anesthesia and Intensive Care, Azienda Sanitaria Universitaria Integrata-Udine, P.le S.Maria Della Misericordia n. 15, 33100, Udine, Italy.

Primary Care Service Barcelonès Nord i Maresme, Catalan Health Institute, Barcelona, Spain.

出版信息

Ultrasound J. 2019 Mar 21;11(1):6. doi: 10.1186/s13089-019-0121-z.

DOI:10.1186/s13089-019-0121-z
PMID:31359291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6638612/
Abstract

The presence of an unknown intracardiac shunt due to a patent foramen ovale may be an unusual cause of hypoxemia. We report the case of a patient who presented persistent hypoxemia after an adequate treatment for a severe asthma attack requiring intensive care unit admission. The patient underwent a transthoracic microbubbles contrast echocardiography that showed a massive patent foramen ovale. The favorable clinical course and the absence of major signs and symptoms related to patent foramen ovale allowed a conservative approach with a follow-up program. Patent foramen ovale should be suspected in case of persistent hypoxemia after a severe asthma attack had resolved.

摘要

卵圆孔未闭导致的不明心脏内分流可能是低氧血症的一个不寻常原因。我们报告一例患者,在因严重哮喘发作接受充分治疗并入住重症监护病房后仍持续存在低氧血症。该患者接受了经胸微泡对比超声心动图检查,结果显示存在巨大卵圆孔未闭。良好的临床病程以及缺乏与卵圆孔未闭相关的主要体征和症状,使得我们采取了保守方法并制定了随访计划。在严重哮喘发作缓解后若仍持续存在低氧血症,应怀疑卵圆孔未闭。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64b1/6638612/c97c9cad05fc/13089_2019_121_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64b1/6638612/c97c9cad05fc/13089_2019_121_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64b1/6638612/c97c9cad05fc/13089_2019_121_Fig1_HTML.jpg

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本文引用的文献

1
Association of Preoperatively Diagnosed Patent Foramen Ovale With Perioperative Ischemic Stroke.术前诊断的卵圆孔未闭与围手术期缺血性卒中的关联。
JAMA. 2018 Feb 6;319(5):452-462. doi: 10.1001/jama.2017.21899.
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Patent foramen ovale: Unanswered questions.卵圆孔未闭:未解之谜。
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Accuracy of conventional transthoracic echocardiography for the diagnosis of intracardiac right-to-left shunt: a meta-analysis of prospective studies.
传统经胸超声心动图诊断心内右向左分流的准确性:前瞻性研究的荟萃分析
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Eur Respir J. 1993 Nov;6(10):1567-8.