中国淡水小龙虾（克氏原螯虾）基因组研究取得新进展
Characterization of the innate immunity in the mud crab Scylla paramamosain.
机构信息
State Key Laboratory of Marine Environmental Science, College of Ocean & Earth Sciences, Xiamen University, Xiamen, Fujian, China; State-Province Joint Engineering Laboratory of Marine Bioproducts and Technology, Xiamen University, Xiamen, Fujian, China; Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen University, Xiamen, Fujian, China.
State Key Laboratory of Marine Environmental Science, College of Ocean & Earth Sciences, Xiamen University, Xiamen, Fujian, China; State-Province Joint Engineering Laboratory of Marine Bioproducts and Technology, Xiamen University, Xiamen, Fujian, China; Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Xiamen University, Xiamen, Fujian, China.
出版信息
Fish Shellfish Immunol. 2019 Oct;93:436-448. doi: 10.1016/j.fsi.2019.07.076. Epub 2019 Jul 27.
Mud crabs, Scylla paramamosain, are one of the most economical and nutritious crab species in China and South Asia. Inconsistent with the high development of commercial mud crab aquaculture, effective immunological methods to prevent frequently-occurring diseases have not yet been developed. Thus, high mortalities often occur throughout the different developmental stages of this species resulting in large economic losses. In recent years, numerous attempts have been made to use various advanced biological technologies to understand the innate immunity of S. paramamosain as well as to characterize specific immune components. This review summarizes these research advances regarding cellular and humoral responses of the mud crab during pathogen infection, highlighting hemocytes and gills defense, pattern recognition, immune-related signaling pathways (Toll, IMD, JAK/STAT, and prophenoloxidase (proPO) cascades), immune effectors (antimicrobial peptides), production of reactive oxygen species and the antioxidant system. Diseases affecting the development of mud crab aquaculture and potential disease control strategies are discussed.
泥蟹，锯缘青蟹，是中国和南亚最经济和营养的蟹种之一。与商业泥蟹养殖业的高度发展不一致的是，尚未开发出有效的免疫方法来预防经常发生的疾病。因此，在该物种的不同发育阶段经常发生高死亡率，导致巨大的经济损失。近年来，人们已经尝试使用各种先进的生物技术来了解锯缘青蟹的先天免疫以及表征特定的免疫成分。本综述总结了泥蟹在病原体感染过程中的细胞和体液反应的这些研究进展，重点介绍了血细胞和鳃防御、模式识别、免疫相关信号通路（Toll、IMD、JAK/STAT 和酚氧化酶（proPO）级联）、免疫效应物（抗菌肽）、活性氧和抗氧化系统的产生。讨论了影响泥蟹养殖业发展的疾病以及潜在的疾病控制策略。
Zotero 插件