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影像学骶髂关节炎的中轴型脊柱关节炎患者是否同时符合改良纽约标准和 ASAS 中轴型脊柱关节炎标准?8 个队列的研究结果。

Do patients with axial spondyloarthritis with radiographic sacroiliitis fulfil both the modified New York criteria and the ASAS axial spondyloarthritis criteria? Results from eight cohorts.

机构信息

Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

Paris Descartes University, Rheumatology, Cochin Hospital, Assistance Publique - Hôpitaux de Paris, Paris, France.

出版信息

Ann Rheum Dis. 2019 Nov;78(11):1545-1549. doi: 10.1136/annrheumdis-2019-215707. Epub 2019 Jul 30.

Abstract

BACKGROUND

Patients with spondyloarthritis with radiographic sacroiliitis are traditionally classified according to the modified New York (mNY) criteria as ankylosing spondylitis (AS) and more recently according to the Assessment of SpondyloArthritis international Society (ASAS) criteria as radiographic axial spondyloarthritis (r-axSpA).

OBJECTIVE

To investigate the agreement between the mNY criteria for AS and the ASAS criteria for r-axSpA and reasons for disagreement.

METHODS

Patients with back pain ≥3 months diagnosed as axSpA with radiographic sacroiliitis (mNY radiographic criterion) were selected from eight cohorts (ASAS, Esperanza, GESPIC, OASIS, Reuma.pt, SCQM, SPACE, UCSF). Subsequently, we calculated the percentage of patients who fulfilled the ASAS r-axSpA criteria within the group of patients who fulfilled the mNY criteria and vice versa in six cohorts with complete information.

RESULTS

Of the 3882 patients fulfilling the mNY criteria, 93% also fulfilled the ASAS r-axSpA criteria. Inversely, of the 3434 patients fulfilling the ASAS r-axSpA criteria, 96% also fulfilled the mNY criteria. The main cause for discrepancy between the two criteria sets was the reported age at onset of back pain.

CONCLUSION

Almost all patients with axSpA with radiographic sacroiliitis fulfil both ASAS and mNY criteria, which supports the interchangeable use of the terms AS and r-axSpA.

摘要

背景

传统上,影像学骶髂关节炎的脊柱关节炎患者根据改良纽约(mNY)标准分为强直性脊柱炎(AS),最近根据评估脊柱关节炎国际学会(ASAS)标准分为放射学中轴型脊柱关节炎(r-axSpA)。

目的

探讨 mNY 标准用于 AS 与 ASAS 标准用于 r-axSpA 的一致性及其不一致的原因。

方法

从 8 个队列(ASAS、Esperanza、GESPIC、OASIS、Reuma.pt、SCQM、SPACE、UCSF)中选择符合 ASAS 中轴型脊柱关节炎伴影像学骶髂关节炎(mNY 影像学标准)且背痛≥3 个月的患者。随后,我们计算了在 6 个有完整信息的队列中,同时符合 mNY 标准和 ASAS r-axSpA 标准的患者比例,以及反之亦然的患者比例。

结果

在符合 mNY 标准的 3882 例患者中,93%也符合 ASAS r-axSpA 标准。相反,在符合 ASAS r-axSpA 标准的 3434 例患者中,96%也符合 mNY 标准。两个标准之间出现差异的主要原因是背痛发病年龄的报告不同。

结论

几乎所有影像学骶髂关节炎的中轴型脊柱关节炎患者均同时符合 ASAS 和 mNY 标准,这支持 AS 和 r-axSpA 这两个术语可以互换使用。

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