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巴贝斯虫病:美国中西部上游地区38例病例的回顾性研究

Babesiosis: A Retrospective Review of 38 Cases in the Upper Midwest.

作者信息

Fida Madiha, Challener Douglas, Hamdi Ahmed, O'horo John, Abu Saleh Omar

机构信息

Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

出版信息

Open Forum Infect Dis. 2019 Jul 1;6(7). doi: 10.1093/ofid/ofz311.

DOI:10.1093/ofid/ofz311
PMID:31363764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6667709/
Abstract

Babesiosis is an emerging health risk, and clinicians need to be aware of its different clinical manifestations. In our cohort of 38 patients, almost half did not recall a tick bite, and diagnosis was delayed due to the nonspecific nature of symptoms. Sixty-eight percent of patients required hospitalization, with 21% requiring intensive care unit stay. Coinfection with Lyme, anaplasma, or both Lyme and anaplasma was seen in 24%, 5%, and 8% of the patients, respectively. None of the patients in our cohort died from their disease.

摘要

巴贝斯虫病是一种新出现的健康风险,临床医生需要了解其不同的临床表现。在我们的38例患者队列中,几乎一半的患者不记得被蜱虫叮咬过,由于症状的非特异性,诊断被延迟。68%的患者需要住院治疗,其中21%的患者需要入住重症监护病房。分别有24%、5%和8%的患者同时感染了莱姆病、无形体病或莱姆病和无形体病。我们队列中的患者均未因该病死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8f/6667709/beff8cb3f8ea/ofz311f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8f/6667709/b573c97bca00/ofz311f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8f/6667709/beff8cb3f8ea/ofz311f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8f/6667709/b573c97bca00/ofz311f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa8f/6667709/beff8cb3f8ea/ofz311f0002.jpg

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Human babesiosis.人巴贝斯虫病。
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纽约州两种感染的流行地区,对聚合酶链反应(PCR)检测呈阳性的全血样本进行PCR检测呈阳性的频率。
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Global Metabolomic Profiling of Host Red Blood Cells Infected with Babesia divergens Reveals Novel Antiparasitic Target Pathways.对感染分歧巴贝斯虫的宿主红细胞进行全球代谢组学分析揭示了新的抗寄生虫靶标途径。
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The Centers for Disease Control and Prevention and State Health Departments should include Blood-Type Variables in their Babesiosis Case Reports.疾病控制与预防中心以及各州卫生部门应在其巴贝斯虫病病例报告中纳入血型变量。
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