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统一卫生系统患者皮肤癣菌病的发病情况

Occurrence of dermatophytoses in patients from the Sistema Único de Saúde.

作者信息

Sanguino Talita Carla, Jarros Isabele Carrilho, Negri Melyssa

机构信息

Department of Clinical Analyses and Biomedicine, Universidade Estadual de Maringá, Maringá (PR), Brazil.

Department of Clinical Analyses and Biomedicine, Laboratory of Medical Mycology, Universidade Estadual de Maringá, Maringá (PR), Brazil.

出版信息

An Bras Dermatol. 2019 Jul 29;94(3):293-297. doi: 10.1590/abd1806-4841.20197491.

Abstract

BACKGROUND

Dermatophytosis is a cutaneous disease caused by filamentous keratinophilic fungi belonging to the genera Trichophyton, Microsporum and Epidermophyton, which present a high prevalence in the general population, being among the most common mycoses affecting about 20% of the world's population.

OBJECTIVE

To carry out the epidemiological survey of cases of dermatophytosis in patients from the Sistema Único de Saúde in a regional Laboratory in the period of 5 years (2009 to 2013).

METHODS

A retrospective study (January 2009 to December 2013) was carried out with a qualitative and quantitative design, through the registry book of the laboratory, Mycology Sector, where cases of patients with suspected dermatomycosis were analyzed.

RESULTS

In a 5-year period, a total of 4467 cases were suspected of having a fungal infection. Of these, 68.74% (3071) cases were of dermatomycosis. In relation to cultures with fungal growth, 12.54% (385 cases) were dermatophyte fungi and 7.97% (245 cases) non-dermatophyte fungi were isolated. Among the species identified, there was a higher prevalence of T. rubrum complex (75%), T. mentagrophytes complex (11.68%) and M. canis (7.01%). Regarding the sites analyzed, nail involvement was the most frequent in 75% of the cases.

STUDY LIMITATIONS

This work is representative in the studied region.

CONCLUSIONS

Dermatomycosis samples are the most frequent among all samples of fungal infections from these patients, with the nail being the most affected area and the fungi T. rubrum complex and T. mentagrophytes complex the most frequent.

摘要

背景

皮肤癣菌病是一种由毛癣菌属、小孢子菌属和表皮癣菌属的嗜角质丝状真菌引起的皮肤疾病,在普通人群中患病率很高,是最常见的真菌病之一,影响着约20%的世界人口。

目的

对某地区实验室5年(2009年至2013年)期间来自单一卫生系统患者的皮肤癣菌病病例进行流行病学调查。

方法

采用回顾性研究(2009年1月至2013年12月),采用定性和定量设计,通过实验室真菌学部门的登记册,分析疑似皮肤癣菌病患者的病例。

结果

在5年期间,共有4467例疑似真菌感染病例。其中,68.74%(3071例)为皮肤癣菌病。在有真菌生长的培养物中,12.54%(385例)为皮肤癣菌,7.97%(245例)为非皮肤癣菌。在鉴定出的菌种中,红色毛癣菌复合体(75%)、须癣毛癣菌复合体(11.68%)和犬小孢子菌(7.01%)的患病率较高。在所分析的部位中,75%的病例指甲受累最为常见。

研究局限性

这项工作在所研究地区具有代表性。

结论

在这些患者的所有真菌感染样本中,皮肤癣菌病样本最为常见,指甲是受影响最严重的部位,红色毛癣菌复合体和须癣毛癣菌复合体是最常见的真菌。

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本文引用的文献

1
The Changing Face of Dermatophytic Infections Worldwide.全球皮肤癣菌感染的变化面貌。
Mycopathologia. 2017 Feb;182(1-2):77-86. doi: 10.1007/s11046-016-0082-8. Epub 2016 Oct 25.
2
Descriptive study of onychomycosis in a hospital in São Paulo.圣保罗一家医院甲癣的描述性研究。
Braz J Microbiol. 2015 Jun 1;46(2):485-92. doi: 10.1590/S1517-838246220130541. eCollection 2015 Jun.
6
Molecular epidemiology, phylogeny and evolution of dermatophytes.皮肤真菌的分子流行病学、系统发育和进化。
Infect Genet Evol. 2013 Dec;20:336-51. doi: 10.1016/j.meegid.2013.09.005. Epub 2013 Sep 20.

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