Department of Preventative Medicine, Northwestern University Feinberg School of Medicine, 680 N Lakeshore Drive, Suite 1400, Chicago, IL, 60611, USA.
Department of Natural and Applied Sciences, Bentley University, Waltham, MA, USA.
Support Care Cancer. 2020 Apr;28(4):1919-1928. doi: 10.1007/s00520-019-05002-w. Epub 2019 Jul 31.
Physical activity has been shown to decline over the course of chemotherapy in breast cancer survivors; yet it may reduce treatment-related side effects and emerging evidence indicates it may improve disease outcomes. Mobile health (mHealth) interventions may be an effective, scalable strategy to increase physical activity during treatment. However, little is known about breast cancer patients' interests and preferences for these interventions. It is important to understand patients' interests and preferences prior to development of mHealth physical activity interventions to increase their relevance and efficacy.
Breast cancer survivors (n = 30) participated in a semi-structured phone interview and were asked about barriers and facilitators to physical activity during chemotherapy as well as their preferences on a range of potential mHealth intervention features. Transcribed interviews were coded and key themes were analyzed using an iterative, inductive approach.
Five key themes were extracted from the interviews: (1) need for education about physical activity during chemotherapy; (2) treatment side effects inhibit physical activity; (3) a structured, home-based, tech-supported program with in-person elements is most feasible; (4) need for a personalized, highly tailored intervention; and (5) importance of social support from other breast cancer survivors, friends, and family.
Breast cancer survivors are interested in mHealth physical activity interventions during chemotherapy, but preferences for intervention content and delivery varied. Future work should engage patients and survivors in intervention development and testing.
研究表明，在乳腺癌幸存者接受化疗的过程中，身体活动会逐渐减少；然而，身体活动可能会减少与治疗相关的副作用，并且新出现的证据表明，它可能改善疾病的结果。移动健康（mHealth）干预措施可能是增加治疗期间身体活动的有效、可扩展策略。然而，对于乳腺癌患者对这些干预措施的兴趣和偏好知之甚少。在开发 mHealth 身体活动干预措施之前，了解患者的兴趣和偏好对于提高其相关性和有效性非常重要。
乳腺癌幸存者（n=30）参加了半结构化电话访谈，被问及在化疗期间进行身体活动的障碍和促进因素，以及他们对一系列潜在 mHealth 干预措施功能的偏好。转录的访谈进行了编码，并使用迭代的、归纳的方法对关键主题进行了分析。
从访谈中提取了五个关键主题：（1）在化疗期间进行身体活动的教育需求；（2）治疗副作用抑制身体活动；（3）一种结构合理、基于家庭、技术支持的方案，结合面对面元素是最可行的；（4）需要个性化、高度定制的干预措施；（5）来自其他乳腺癌幸存者、朋友和家人的社会支持的重要性。
乳腺癌幸存者对化疗期间的 mHealth 身体活动干预措施感兴趣，但对干预内容和交付方式的偏好存在差异。未来的工作应该让患者和幸存者参与干预措施的开发和测试。
