Ricketts Emily J, Snorrason Ivar, Kircanski Katharina, Alexander Jennifer R, Stiede Jordan T, Thamrin Hardian, Flessner Christopher A, Franklin Martin E, Keuthen Nancy J, Walther Michael R, Piacentini John, Stein Dan J, Woods Douglas W
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90024-5055 USA. E-MAIL:
Ann Clin Psychiatry. 2019 Aug;31(3):169-178.
Trichotillomania (TTM) onset may occur across the lifespan; however, adolescent onset is most frequently reported. Several studies have explored clinical differences between TTM age-of-onset groups with mixed results. We investigated empirically defined age-of-onset groups in adults with TTM, and clinical differences between groups.
Participants included 1,604 adult respondents to an internet survey who endorsed DSM-IV-TR TTM criteria. Latent profile analysis was performed to identify TTM age-of-onset subgroups, which were then compared on demographic and clinical features.
The most optimal model was a 2-class solution comprised of a large group with average TTM onset during adolescence (n = 1,539; 95.9% of the sample; mean age of onset = 12.4) and a small group with average onset in middle adulthood (n = 65; 4.1% of the sample; mean age of onset = 35.6). The late-onset group differed from the early-onset group on several clinical variables (eg, less likely to report co-occurring bodyfocused repetitive behaviors).
Findings suggest the presence of at least 2 distinct TTM age-of-onset subgroups: an early-onset group with onset during adolescence, and a late-onset group with onset in middle adulthood. Future research is needed to further validate these subgroups and explore their clinical utility.
拔毛癖(TTM)可在人的一生中任何时候发病;然而,最常报告的发病年龄是青少年期。多项研究探讨了拔毛癖不同发病年龄组之间的临床差异,但结果不一。我们对根据经验定义的成年拔毛癖患者发病年龄组及其组间临床差异进行了调查。
参与者包括1604名通过网络调查认可《精神疾病诊断与统计手册》第四版修订版(DSM-IV-TR)拔毛癖标准的成年受访者。进行潜在剖面分析以确定拔毛癖发病年龄亚组,然后比较这些亚组在人口统计学和临床特征方面的差异。
最优模型是一个两类解决方案,其中一大组患者在青春期平均发病(n = 1539;占样本的95.9%;平均发病年龄 = 12.4岁),一小组患者在成年中期平均发病(n = 65;占样本的4.1%;平均发病年龄 = 35.6岁)。晚发组在几个临床变量上与早发组不同(例如,报告同时存在身体聚焦重复行为的可能性较小)。
研究结果表明至少存在两个不同的拔毛癖发病年龄亚组:一个是青春期发病的早发组,另一个是成年中期发病的晚发组。未来需要进一步研究以验证这些亚组并探索其临床应用价值。