Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Internal Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Int J Infect Dis. 2019 Oct;87:75-83. doi: 10.1016/j.ijid.2019.07.016. Epub 2019 Jul 29.
Pertussis is a highly infectious respiratory disease caused by Bordetella pertussis. Infants and young children are particularly at risk of severe and life-threatening disease. Infectious older individuals may transmit Bordetella pertussis to unprotected infants. Pertussis control measures have even failed in some countries with high pertussis vaccination coverage rates, leading to increased incidence rates. In 2014, this caused the World Health Organization to declare pertussis resurgent in some countries and led to recommendations regarding pertussis surveillance and national immunization programs. Despite the resurgence of pertussis, epidemiology of the disease in Southeast Asia has received little attention. In this narrative review, we describe pertussis surveillance systems, control measures, epidemiologic trends, and region-specific pertussis research in Southeast Asia. We also make recommendations for the intensification of pertussis surveillance and research in the region.
百日咳是由百日咳博德特氏菌引起的高度传染性呼吸道疾病。婴儿和幼儿特别容易患严重和危及生命的疾病。具有传染性的年长个体可能会将百日咳博德特氏菌传播给未受保护的婴儿。即使在百日咳疫苗接种率较高的一些国家，百日咳控制措施也已经失败，导致发病率上升。2014 年，世界卫生组织宣布一些国家的百日咳疫情死灰复燃，并就百日咳监测和国家免疫规划提出了建议。尽管百日咳再次出现，但东南亚的疾病流行病学仍未受到关注。在这篇叙述性综述中，我们描述了东南亚的百日咳监测系统、控制措施、流行病学趋势和特定于该地区的百日咳研究。我们还为该地区加强百日咳监测和研究提出了建议。
