Wahlström G, Pear W S, Steen M L, Szpirer J, Levan G, Klein G, Sümegi J
Department of Tumor Biology, Karolinska Institute, Stockholm, Sweden.
Immunogenetics. 1988;28(3):182-3. doi: 10.1007/BF00375857.
Previous experiments using rat/mouse somatic cell hybrids have localized the rat c-myc gene to chromosome 7 (Sümegi et al. 1983), the rat immunoglobulin kappa locus to chromosome 4 (Perlmann et al. 1985), and the rat immunoglobulin heavy chain locus to chromosome 6 (Pear et al. 1986). Using a similar approach, we now report the localization of the rat immunoglobulin lambda light chain locus to chromosome 11.
以往利用大鼠/小鼠体细胞杂种进行的实验已将大鼠c-myc基因定位到7号染色体(苏梅吉等人,1983年),将大鼠免疫球蛋白κ基因座定位到4号染色体(佩尔曼等人,1985年),并将大鼠免疫球蛋白重链基因座定位到6号染色体(皮尔等人,1986年)。采用类似方法,我们现在报告大鼠免疫球蛋白λ轻链基因座定位到11号染色体。