School of Pharmacy , Nantong University , 19 Qixiu Road , Nantong , Jiangsu Province 226001 , People's Republic of China.
Org Lett. 2019 Aug 16;21(16):6548-6551. doi: 10.1021/acs.orglett.9b02492. Epub 2019 Aug 2.
Evolvulins I and II ( and ), representing a new class of resin glycosides with an unprecedented trihydroxy aglycone unit, 3,11,14-trihydroxyhexadecanoic acid (), were isolated from the whole plants of . Their structures were thoroughly characterized by extensive spectroscopic analyses as well as chemical evidence. Compound exhibited the most potent cytotoxic activity against MCF-7 cells, with an IC value of 3.12 μM.
螺旋甾烷醇类 I 和 II（和），代表了一类具有前所未有的三羟基糖基单元的新型树脂糖苷，3,11,14-三羟基十六烷酸（），从的全植物中分离得到。通过广泛的光谱分析以及化学证据，对它们的结构进行了彻底的表征。化合物表现出对 MCF-7 细胞最强的细胞毒性活性，IC 值为 3.12 μM。
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