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一种用于测量心电图、心震图和心脏时间间期的胸部层压超薄可拉伸电子纹身。

A Chest-Laminated Ultrathin and Stretchable E-Tattoo for the Measurement of Electrocardiogram, Seismocardiogram, and Cardiac Time Intervals.

作者信息

Ha Taewoo, Tran Jason, Liu Siyi, Jang Hongwoo, Jeong Hyoyoung, Mitbander Ruchika, Huh Heeyong, Qiu Yitao, Duong Jason, Wang Rebecca L, Wang Pulin, Tandon Animesh, Sirohi Jayant, Lu Nanshu

机构信息

Department of Electrical and Computer Engineering University of Texas at Austin TX 78712 USA.

Department of Aerospace Engineering and Engineering Mechanics University of Texas at Austin TX 78712 USA.

出版信息

Adv Sci (Weinh). 2019 May 21;6(14):1900290. doi: 10.1002/advs.201900290. eCollection 2019 Jul 17.

Abstract

Seismocardiography (SCG) is a measure of chest vibration associated with heartbeats. While skin soft electronic tattoos (e-tattoos) have been widely reported for electrocardiogram (ECG) sensing, wearable SCG sensors are still based on either rigid accelerometers or non-stretchable piezoelectric membranes. This work reports an ultrathin and stretchable SCG sensing e-tattoo based on the filamentary serpentine mesh of 28-µm-thick piezoelectric polymer, polyvinylidene fluoride (PVDF). 3D digital image correlation (DIC) is used to map chest vibration to identify the best location to mount the e-tattoo and to investigate the effects of substrate stiffness. As piezoelectric sensors easily suffer from motion artifacts, motion artifacts are effectively reduced by performing subtraction between a pair of identical SCG tattoos placed adjacent to each other. Integrating the soft SCG sensor with a pair of soft gold electrodes on a single e-tattoo platform forms a soft electro-mechano-acoustic cardiovascular (EMAC) sensing tattoo, which can perform synchronous ECG and SCG measurements and extract various cardiac time intervals including systolic time interval (STI). Using the EMAC tattoo, strong correlations between STI and the systolic/diastolic blood pressures, are found, which may provide a simple way to estimate blood pressure continuously and noninvasively using one chest-mounted e-tattoo.

摘要

地震心音描记术(SCG)是一种测量与心跳相关的胸部振动的方法。虽然皮肤柔软的电子纹身(e纹身)已被广泛报道用于心电图(ECG)传感,但可穿戴的SCG传感器仍基于刚性加速度计或不可拉伸的压电膜。这项工作报道了一种基于28微米厚的压电聚合物聚偏二氟乙烯(PVDF)的丝状蛇形网格的超薄且可拉伸的SCG传感e纹身。三维数字图像相关(DIC)用于绘制胸部振动图,以确定安装e纹身的最佳位置,并研究基底刚度的影响。由于压电传感器容易受到运动伪影的影响,通过在彼此相邻放置的一对相同的SCG纹身之间进行减法运算,可以有效减少运动伪影。将软SCG传感器与一对软金电极集成在单个e纹身平台上,形成了一种柔软的机电声心血管(EMAC)传感纹身,它可以同步进行ECG和SCG测量,并提取包括收缩期时间间隔(STI)在内的各种心脏时间间隔。使用EMAC纹身,发现STI与收缩压/舒张压之间存在强相关性,这可能提供一种使用一个胸部佩戴的e纹身连续且无创地估计血压的简单方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bec4/6662084/bdfdd4d19e94/ADVS-6-1900290-g001.jpg

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