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原发性干燥综合征的蒙特利尔认知评估。一种简短的筛查工具。

Montreal cognitive assessment in primary sjogrens syndrome. A brief screening tool.

作者信息

Kurtulus Fatma, Cay Hasan F, Parlak Eda, Yaman Aylin

机构信息

Department of Neurology, Antalya Education and Research Hospital, Antalya,Turkey. E-mail:

出版信息

Neurosciences (Riyadh). 2019 Jul;24(3):199-206. doi: 10.17712/nsj.2019.3.20180027.

DOI:10.17712/nsj.2019.3.20180027
PMID:31380819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8015506/
Abstract

OBJECTIVE

To use the Montreal Cognitive Assessment (MoCA) test to assess the subclinical cognitive impairment in patients with Primary Sjogren`s Syndrome (PSS) and assess the correlation of MoCA results with magnetic resonance imaging (MRI) findings in these patients.

METHODS

The MoCA test was prospectively administered to 32 consecutive patients (31 females, 1 male) diagnosed with PSS and 30 healthy controls (29 females, 1 male) at Antalya Education and Research Hospital between June 2014 and October 2015. Twenty PSS patients underwent a brain MRI (T1, T2, and T2- FLAIR-weighted sequences).

RESULTS

The mean age was 45.84 (range 24-63) in the PSS group, and the mean duration of disease was 3.5 years (4 months - 18 years). There were 22 patients (68.80%) with 5-8 years of education and 10 patients (31.30%) with more than 8 years of education. The mean age was 42.8 (28-64) in the control group. There were 20 controls (66.70%) with 5-8 years of education and 10 controls (33.3%) with more than 8 years of education. The delayed recall rate of the patient group with 5-8 years of education was significantly lower than that of the control group, and the recall rate with multiple choice cues for the same patient group was significantly higher than that of the control group (p less than 0.05). There was no correlation between the number of lesions and total MoCA score or subgroups.

CONCLUSION

We suggest that the MoCA test is a single-page, easy-to-administer test, can be used to assess cognition in patients with PSS especially in large groups.

摘要

目的

使用蒙特利尔认知评估(MoCA)测试评估原发性干燥综合征(PSS)患者的亚临床认知障碍,并评估MoCA结果与这些患者磁共振成像(MRI)结果的相关性。

方法

2014年6月至2015年10月期间,在安塔利亚教育与研究医院对32例连续诊断为PSS的患者(31例女性,1例男性)和30例健康对照者(29例女性,1例男性)前瞻性地进行MoCA测试。20例PSS患者接受了脑部MRI检查(T1、T2和T2-FLAIR加权序列)。

结果

PSS组的平均年龄为45.84岁(范围24-63岁),平均病程为3.5年(4个月-18年)。有22例患者(68.80%)接受教育5-8年,10例患者(31.30%)接受教育超过8年。对照组的平均年龄为42.8岁(28-64岁)。有20例对照者(66.70%)接受教育5-8年,10例对照者(33.3%)接受教育超过8年。接受教育5-8年的患者组延迟回忆率显著低于对照组,同一患者组多项选择提示下的回忆率显著高于对照组(p<0.05)。病变数量与MoCA总分或亚组之间无相关性。

结论

我们认为MoCA测试是一种单页、易于实施的测试,可用于评估PSS患者的认知,尤其是在大群体中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c3/8015506/56b3a145f6dc/Neurosciences-24-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c3/8015506/56b3a145f6dc/Neurosciences-24-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c3/8015506/56b3a145f6dc/Neurosciences-24-199-g001.jpg

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