• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

利奈唑胺致一名广泛耐药结核病患儿视神经病变：病例报告及文献复习

Linezolid induced optic neuropathy in a child treated for extensively drug resistant tuberculosis: A case report and review of literature.

作者信息

Agashe Prachi, Doshi Ashish

机构信息

K.B. Haji Bachooali Eye Hospital, 58/60, Jehangir Merwanji Street, Opposite K.E.M Hospital, Parel, Mumbai 400012, India.

Advanced Eye Hospital and Institute, 30, The Affaires, Palm Beach Road, Sector-17, Sanpada, Navi Mumbai 400 705, India.

出版信息

Saudi J Ophthalmol. 2019 Apr-Jun;33(2):188-191. doi: 10.1016/j.sjopt.2018.10.010. Epub 2018 Nov 3.

DOI:10.1016/j.sjopt.2018.10.010
PMID:31384167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6664266/
Abstract

Linezolid induced optic neuropathy occurring after prolonged use of the drug is rarely reported in the paediatric age group. We report a case of Linezolid induced optic neuropathy in a child treated for extensively drug resistant tuberculosis. The optic neuropathy completely reversed with good improvement in vision after stopping the drug, which to the best of our knowledge has not been reported before.

摘要

长期使用利奈唑胺后引发的视神经病变在儿童年龄组中鲜有报道。我们报告了一例在治疗广泛耐药结核病的儿童中发生的利奈唑胺诱导的视神经病变。停用药物后，视神经病变完全逆转，视力有显著改善，据我们所知，此前尚未有过此类报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e6/6664266/ef1b534c8190/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e6/6664266/9d7962035470/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e6/6664266/ef1b534c8190/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e6/6664266/9d7962035470/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7e6/6664266/ef1b534c8190/gr2.jpg

相似文献

1
Linezolid induced optic neuropathy in a child treated for extensively drug resistant tuberculosis: A case report and review of literature.利奈唑胺致一名广泛耐药结核病患儿视神经病变：病例报告及文献复习
Saudi J Ophthalmol. 2019 Apr-Jun;33(2):188-191. doi: 10.1016/j.sjopt.2018.10.010. Epub 2018 Nov 3.
2
Peripheral neuropathy in a diabetic child treated with linezolid for multidrug-resistant tuberculosis: a case report and review of the literature.利奈唑胺治疗耐多药结核病的糖尿病儿童发生周围神经病变：一例报告及文献复习
BMC Infect Dis. 2017 Jun 12;17(1):417. doi: 10.1186/s12879-017-2499-1.
3
Linezolid-induced optic neuropathy in XDR pulmonary TB: A case series.利奈唑胺所致广泛耐药性肺结核患者视神经病变：病例系列报告
Indian J Tuberc. 2017 Apr;64(2):129-133. doi: 10.1016/j.ijtb.2016.11.010. Epub 2017 Jan 2.
4
A Case Report and Literature Review of the Outcome of Linezolid-Induced Optic and Peripheral Neuropathy in Patients With Multidrug-Resistant Pulmonary TB.耐多药肺结核患者利奈唑胺所致视神经和周围神经病变结局的病例报告及文献综述
Front Neurol. 2022 Jun 24;13:908584. doi: 10.3389/fneur.2022.908584. eCollection 2022.
5
Linezolid-Induced Toxic Optic Neuropathy.利奈唑胺致中毒性视神经病变。
Middle East Afr J Ophthalmol. 2021 Jan 19;27(4):235-237. doi: 10.4103/meajo.MEAJO_73_20. eCollection 2020 Oct-Dec.
6
Linezolid optic neuropathy.利奈唑胺致 optic neuropathy。
Curr Opin Ophthalmol. 2023 Nov 1;34(6):481-486. doi: 10.1097/ICU.0000000000000995. Epub 2023 Aug 21.
7
Is Severe and Long-lasting Linezolid-induced Optic Neuropathy Reversible?严重且持久的利奈唑胺诱导的视神经病变可逆吗？
Intern Med. 2018 Dec 15;57(24):3611-3613. doi: 10.2169/internalmedicine.1344-18. Epub 2018 Aug 10.
8
Optic neuropathy secondary to Linezolid for multidrug-resistant mycobacterial spinal tuberculosis.利奈唑胺继发视神经病变用于耐多药分枝杆菌性脊柱结核
Ocul Immunol Inflamm. 2015 Feb;23(1):90-2. doi: 10.3109/09273948.2013.874447. Epub 2014 Jan 16.
9
Linezolid-Associated Optic Neuropathy in Drug-Resistant Tuberculosis Patients in Mumbai, India.印度孟买耐药结核病患者中与利奈唑胺相关的视神经病变
PLoS One. 2016 Sep 9;11(9):e0162138. doi: 10.1371/journal.pone.0162138. eCollection 2016.
10
Drug-induced optic neuropathy in a case of extensively drug-resistant pulmonary tuberculosis.广泛耐药性肺结核病例中的药物性视神经病变
J Basic Clin Physiol Pharmacol. 2018 Dec 19;30(1):139-140. doi: 10.1515/jbcpp-2018-0007.

引用本文的文献

1
Case Report: Linezolid-associated toxic optic neuropathy in patients with pulmonary tuberculosis: case series and mini review.病例报告：肺结核患者中与利奈唑胺相关的中毒性视神经病变：病例系列及小型综述
Front Pharmacol. 2025 May 13;16:1547236. doi: 10.3389/fphar.2025.1547236. eCollection 2025.
2
Neuromyelitis optica causing vision loss during TB treatment with sutezolid: evidence of aberrant immunity following infection.在使用舒替利唑胺治疗结核病期间，视神经脊髓炎导致视力丧失：感染后异常免疫的证据。
IJTLD Open. 2025 May 12;2(5):306-309. doi: 10.5588/ijtldopen.25.0071. eCollection 2025 May.
3
A Case Report and Literature Review of the Outcome of Linezolid-Induced Optic and Peripheral Neuropathy in Patients With Multidrug-Resistant Pulmonary TB.

本文引用的文献

1
Linezolid-associated optic neuropathy in a pediatric patient with Mycobacterium nonchromogenicum: A case report.一名患有非产色分枝杆菌的儿科患者出现与利奈唑胺相关的视神经病变：病例报告。
Medicine (Baltimore). 2017 Dec;96(50):e9200. doi: 10.1097/MD.0000000000009200.
2
Linezolid-induced optic neuropathy in XDR pulmonary TB: A case series.利奈唑胺所致广泛耐药性肺结核患者视神经病变：病例系列报告
Indian J Tuberc. 2017 Apr;64(2):129-133. doi: 10.1016/j.ijtb.2016.11.010. Epub 2017 Jan 2.
3
Clinical recovery in linezolid-induced optic nerve toxicity.
耐多药肺结核患者利奈唑胺所致视神经和周围神经病变结局的病例报告及文献综述
Front Neurol. 2022 Jun 24;13:908584. doi: 10.3389/fneur.2022.908584. eCollection 2022.
4
Peripheral neuropathy from use of linezolid and metronidazole in a pediatric patient.一名儿科患者因使用利奈唑胺和甲硝唑导致周围神经病变。
IDCases. 2021 Jun 29;25:e01210. doi: 10.1016/j.idcr.2021.e01210. eCollection 2021.
利奈唑胺所致视神经毒性的临床恢复情况。
Acta Ophthalmol. 2017 Jun;95(4):e341-e342. doi: 10.1111/aos.13237. Epub 2016 Sep 29.
4
Optic neuropathy secondary to Linezolid for multidrug-resistant mycobacterial spinal tuberculosis.利奈唑胺继发视神经病变用于耐多药分枝杆菌性脊柱结核
Ocul Immunol Inflamm. 2015 Feb;23(1):90-2. doi: 10.3109/09273948.2013.874447. Epub 2014 Jan 16.
5
Linezolid-induced optic neuropathy.利奈唑胺所致视神经病变。
Indian J Ophthalmol. 2014 Apr;62(4):497-500. doi: 10.4103/0301-4738.118451.
6
Linezolid-associated optic neuropathy in a patient with drug-resistant tuberculosis.一名耐多药结核病患者出现的与利奈唑胺相关的视神经病变。
J Neuroophthalmol. 2013 Sep;33(3):316-8. doi: 10.1097/WNO.0b013e31829b4265.
7
Drug-related mitochondrial optic neuropathies.药物相关性线粒体视神经病变。
J Neuroophthalmol. 2013 Jun;33(2):172-8. doi: 10.1097/WNO.0b013e3182901969.
8
Linezolid-associated peripheral and optic neuropathy in children.儿童利奈唑胺相关性周围及视神经病变。
Pediatrics. 2011 Jun;127(6):e1528-32. doi: 10.1542/peds.2010-2125. Epub 2011 May 9.
9
Vision impairment in tuberculous meningitis: predictors and prognosis.结核性脑膜炎的视力障碍：预测因素和预后。
J Neurol Sci. 2010 Mar 15;290(1-2):27-32. doi: 10.1016/j.jns.2009.12.012. Epub 2010 Jan 6.
10
A case of optic neuropathy after short-term linezolid use in a patient with acute lymphocytic leukemia.1例急性淋巴细胞白血病患者短期使用利奈唑胺后发生视神经病变的病例。
Clin Infect Dis. 2009 Apr 1;48(7):e73-4. doi: 10.1086/597298.