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A Comprehensive Review of Cannabis in Patients with Cancer: Availability in the USA, General Efficacy, and Safety.癌症患者大麻使用的全面综述:美国的可获得性、一般疗效和安全性。
Curr Oncol Rep. 2019 Feb 1;21(1):10. doi: 10.1007/s11912-019-0757-7.
2
Medical Marijuana Use in a Community Cancer Center.医用大麻在社区癌症中心的使用。
J Oncol Pract. 2018 Sep;14(9):e566-e578. doi: 10.1200/JOP.18.00057.
3
Association of Marijuana Use With Psychosocial and Quality of Life Outcomes Among Patients With Head and Neck Cancer.大麻使用与头颈部癌症患者的心理社会和生活质量结果的关联。
JAMA Otolaryngol Head Neck Surg. 2018 Nov 1;144(11):1017-1022. doi: 10.1001/jamaoto.2018.0486.
4
Marijuana's Influence on Pain Scores, Initial Weight Loss, and Other Bariatric Surgical Outcomes.大麻对疼痛评分、初始体重减轻及其他减肥手术结果的影响。
Perm J. 2018;22:18-002. doi: 10.7812/TPP/18-002.
5
Medical cannabis legalization and opioid prescriptions: evidence on US Medicaid enrollees during 1993-2014.医疗大麻合法化与阿片类药物处方:1993-2014 年美国医疗补助计划参保者相关证据。
Addiction. 2018 Nov;113(11):2060-2070. doi: 10.1111/add.14382. Epub 2018 Aug 6.
6
Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study.慢性非癌痛患者使用大麻对阿片类药物处方的影响:一项为期 4 年的前瞻性队列研究结果。
Lancet Public Health. 2018 Jul;3(7):e341-e350. doi: 10.1016/S2468-2667(18)30110-5.
7
Medical Oncologists' Beliefs, Practices, and Knowledge Regarding Marijuana Used Therapeutically: A Nationally Representative Survey Study.医学肿瘤学家对大麻治疗用途的信念、实践和知识:一项全国代表性调查研究。
J Clin Oncol. 2018 Jul 1;36(19):1957-1962. doi: 10.1200/JCO.2017.76.1221. Epub 2018 May 10.
8
Association Between US State Medical Cannabis Laws and Opioid Prescribing in the Medicare Part D Population.美国州医疗大麻法律与医疗保险处方中阿片类药物开方之间的关联。
JAMA Intern Med. 2018 May 1;178(5):667-672. doi: 10.1001/jamainternmed.2018.0266.
9
Association of Medical and Adult-Use Marijuana Laws With Opioid Prescribing for Medicaid Enrollees.医疗用大麻和成人使用大麻法律与医疗补助计划参保者开阿片类药物处方的关联。
JAMA Intern Med. 2018 May 1;178(5):673-679. doi: 10.1001/jamainternmed.2018.1007.
10
Personalized Pain Goal as an Outcome Measure in Routine Cancer Pain Assessment.个性化疼痛目标作为常规癌症疼痛评估的结果测量指标。
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在一个大麻合法化和非合法化的州,癌症患者对医用大麻的态度和看法以及对其合法化的态度。

Attitudes and Beliefs About Medical Usefulness and Legalization of Marijuana among Cancer Patients in a Legalized and a Nonlegalized State.

机构信息

Department of Palliative, Rehabilitation, and Integrative Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.

Subspecialty Palliative Care in Medical Oncology, Banner MD Anderson Cancer Center, Gilbert, Arizona.

出版信息

J Palliat Med. 2019 Oct;22(10):1213-1220. doi: 10.1089/jpm.2019.0218. Epub 2019 Aug 6.

DOI:10.1089/jpm.2019.0218
PMID:31386595
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7364300/
Abstract

There is a growing preference for the use of marijuana for medical purposes, despite limited evidence regarding its benefits and potential safety risks. Legalization status may play a role in the attitudes and preferences toward medical marijuana (MM). The attitudes and beliefs of cancer patients in a legalized (Arizona) versus nonlegalized state (Texas) regarding medical and recreational legalization and medical usefulness of marijuana were compared. Two hundred adult cancer patients were enrolled from outpatient Palliative Care centers at Banner MD Anderson Cancer Center in Gilbert, AZ ( = 100) and The University of Texas MD Anderson Cancer Center in Houston, TX ( = 100). Adult cancer patients seen by the Palliative Care teams in the outpatient centers were evaluated. Various physical and psychosocial assessments were conducted, including a survey of attitudes and beliefs toward marijuana. The majority of individuals support legalization of marijuana for medical use (Arizona 92% [85-97%] vs. Texas 90% [82-95%];  = 0.81) and belief in its medical usefulness (Arizona 97% [92-99%] vs. Texas 93% [86-97%];  = 0.33) in both states. Overall, 181 (91%) patients supported legalization for medical purposes whereas 80 (40%) supported it for recreational purposes ( < 0.0001). Patients preferred marijuana over current standard treatments for anxiety (60% [51-68%];  = 0.003). Patients found to favor legalizing MM were younger ( = 0.027), had worse fatigue ( = 0.015), appetite ( = 0.004), anxiety ( = 0.017), and were Cut Down, Annoyed, Guilty, and Eye Opener-Adapted to Include Drugs (CAGE-AID) positive for alcohol/drugs ( < 0.0001). Cancer patients from both legalized and nonlegalized states supported legalization of marijuana for medical purposes and believed in its medical use. The support for legalization for medical use was significantly higher than for recreational use in both states.

摘要

尽管关于大麻的益处和潜在安全风险的证据有限,但人们越来越倾向于将其用于医疗用途。大麻的合法化地位可能会影响人们对医用大麻(MM)的态度和偏好。本研究比较了在合法化(亚利桑那州)和非合法化(德克萨斯州)州的癌症患者对医用和娱乐用大麻合法化以及大麻药用价值的态度和看法。从 Banner MD Anderson 癌症中心吉尔伯特姑息治疗中心(亚利桑那州)和休斯顿德克萨斯大学 MD Anderson 癌症中心(德克萨斯州)的门诊患者中招募了 200 名成年癌症患者。姑息治疗小组评估了门诊中心的成年癌症患者。进行了各种身体和社会心理评估,包括对大麻的态度和看法进行了调查。大多数人支持医用大麻合法化(亚利桑那州 92%[85-97%],德克萨斯州 90%[82-95%]; = 0.81)和相信其药用价值(亚利桑那州 97%[92-99%],德克萨斯州 93%[86-97%]; = 0.33)。总体而言,181 名(91%)患者支持医用大麻合法化,80 名(40%)支持娱乐用大麻合法化( < 0.0001)。与当前的焦虑标准治疗相比,患者更倾向于使用大麻(60%[51-68%]; = 0.003)。发现赞成医用 MM 合法化的患者更年轻( = 0.027),疲劳感更严重( = 0.015),食欲( = 0.004),焦虑( = 0.017),以及酒精/药物 Cut Down,Annoyed,Guilty,and Eye Opener-Adapted to Include Drugs(CAGE-AID)评分阳性( < 0.0001)。来自合法化和非合法化州的癌症患者都支持医用大麻合法化,并相信其医疗用途。在两个州,医用大麻合法化的支持率显著高于娱乐用大麻合法化的支持率。