Mazumdar Deepmala, Meethal Najiya S Kadavath, Panday Manish, Asokan Rashima, Thepass Gijs, George Ronnie J, van der Steen Johannes, Pel Johan J M
Vestibular and Ocular Motor Research Group, Department of Neuroscience, Erasmus MC, the Netherlands.
Medical and Vision Research Foundation, Chennai, India.
Transl Vis Sci Technol. 2019 Jul 30;8(4):13. doi: 10.1167/tvst.8.4.13. eCollection 2019 Jul.
In eye movement perimetry (EMP), the extent of the visual field is tested by assessing the saccades using an eye tracker. The aim of the present study was to determine the effects of age and sex of the subjects, the eccentricity and intensity of the peripheral stimuli on saccadic reaction time (SRT), and the interaction between these parameters in healthy participants.
Healthy participants aged between 20 to 70 years underwent a complete ophthalmic examination and an EMP test. SRT was determined from detected peripheral stimuli of four intensity levels. A multilevel mixed-model analysis was used to verify the influence of subject and stimulus characteristics on SRT within the tested visual field.
Ninety-five subjects (mean age 43.0 [15.0] years) were included. Age, stimulus intensity, and eccentricity had a statistically significant effect on SRT, not sex. SRTs were significantly faster with increasing stimulus intensity and decreasing eccentricity ( < 0.001). At the lowest stimulus intensity of 192 cd/m, a significant interaction was found between age and eccentricity.
The current study demonstrated significant SRT dependence across the visual field measured up to 27°, irrespective of sex. The presented SRT values may serve as a first normative guide for EMP.
This report of SRT interaction can aid in refining its use as a measure of visual field responsiveness.
在眼动视野计（EMP）中，通过使用眼动追踪器评估扫视来测试视野范围。本研究的目的是确定受试者的年龄和性别、周边刺激的离心度和强度对扫视反应时间（SRT）的影响，以及这些参数在健康参与者中的相互作用。
年龄在20至70岁之间的健康参与者接受了全面的眼科检查和EMP测试。SRT由检测到的四个强度水平的周边刺激确定。采用多级混合模型分析来验证受试者和刺激特征对测试视野内SRT的影响。
纳入95名受试者（平均年龄43.0 [15.0]岁）。年龄、刺激强度和离心度对SRT有统计学显著影响，而性别没有。随着刺激强度增加和离心度降低，SRT显著加快（<0.001）。在最低刺激强度192 cd/m²时，发现年龄和离心度之间存在显著相互作用。
当前研究表明，在测量范围达27°的视野中，SRT存在显著相关性，与性别无关。所呈现的SRT值可作为EMP的首个规范指南。
本关于SRT相互作用的报告有助于完善其作为视野反应性测量指标的应用。
