Medical and Pharmaceutical Sciences Center, Western Paraná State University, Cascavel, Brazil.
Engineering and Exact Sciences Center, Western Paraná State University, Toledo, Brasil.
J Cosmet Dermatol. 2020 Jan;19(1):33-37. doi: 10.1111/jocd.13093. Epub 2019 Aug 7.
Currently, there is a great interest in cosmetics prepared on natural resources bases and this may restrict the use of synthetic substances. Plants play a relevant role as a source of biologically active natural products with cosmetic and dermatological importance. According to this context, polyphenolic extracts are highlighted because they have proven antioxidant, anti-inflammatory, anti-aging, antimicrobial, and supporting activity in solar photoprotection.
The purpose this study were reviewed at reporting the antioxidant activity of phenolic compounds, mainly applied to dermatological therapy, and highlighting the action mechanisms and structure-activity relationship.
In September 2017, we performed a literature search in PubMed and Scielo for scientific researches, antioxidant studies, and systemic reviews. The search terms we used were "PHYTOCOSMETICS" AND "ANTIOXIDANT ACTIVITY" OR "PHENOLIC COMPOUNDS" (from 2000). As inclusion criteria were used relevant original articles, scientific research in the area of interest, and crucial reference articles. Exclusion criteria were: duplicate publications, non-relevant articles and not published in English.
The potential cosmetic application of phenolic compounds as natural antioxidants has been attributed to the chemical structure of these compounds, which to interfere in different phases of the oxidation mechanism.
The use of phenolic extracts emerges as a viable alternative for cosmetic application, ensuring a commitment to sustainability. However, it is of crucial importance to evaluate the toxicity risks of raw materials and finished products.
目前,人们对基于自然资源制备的化妆品非常感兴趣,这可能会限制合成物质的使用。植物作为具有化妆品和皮肤科重要意义的生物活性天然产物的来源,发挥着重要作用。在此背景下,多酚提取物备受关注,因为它们已被证明具有抗氧化、抗炎、抗老化、抗菌和支持太阳能光保护的活性。
本研究旨在报告酚类化合物的抗氧化活性,主要应用于皮肤科治疗,并强调其作用机制和构效关系。
2017 年 9 月,我们在 PubMed 和 Scielo 上进行了文献检索,以获取有关植物化妆品学和抗氧化活性或酚类化合物的科学研究、抗氧化研究和系统评价。我们使用的检索词是“PHYTOCOSMETICS”和“ANTIOXIDANT ACTIVITY”或“PHENOLIC COMPOUNDS”(从 2000 年开始)。纳入标准是相关的原始文章、该领域的科学研究和关键参考文章。排除标准是:重复发表的文章、不相关的文章和非英文发表的文章。
酚类化合物作为天然抗氧化剂在化妆品中的潜在应用归因于这些化合物的化学结构,这些结构可以干扰氧化机制的不同阶段。
使用酚类提取物作为化妆品应用是一种可行的替代方案,确保了对可持续性的承诺。然而,评估原材料和成品的毒性风险至关重要。