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食源性李斯特菌病。世界卫生组织工作组

Foodborne listeriosis. WHO Working Group.

出版信息

Bull World Health Organ. 1988;66(4):421-8.

Abstract

Listeria monocytogenes is widely distributed in the environment and may be transmitted to man through contamination of foodstuffs at any point from source to kitchen. Milk and dairy products, meat, poultry, vegetables, salads and seafoods have all been found to be contaminated. Unlike most other foodborne pathogens, L. monocytogenes can multiply in refrigerators (4-6 degrees C). Pasteurization reduces their numbers in raw milk to levels that do not pose an appreciable risk to human health.The infection has relatively low morbidity but a high case fatality. At greatest risk are pregnant women and the unborn child, alcoholics, drug abusers, diabetics, patients receiving treatment which alters their natural immunity, AIDS patients, and the elderly. Surveillance systems in countries should monitor sporadic cases and outbreaks of human listeriosis, with the support of a network of reference laboratories for sero-, phage- and other forms of typing at local, national and international levels.The Working Group made recommendations for action by public health authorities and by the food industry in order to control and prevent these infections.

摘要

单核细胞增生李斯特菌在环境中广泛分布,可在从源头到厨房的任何环节通过食品污染传播给人类。已发现牛奶及奶制品、肉类、家禽、蔬菜、沙拉和海鲜均受到污染。与大多数其他食源性病原体不同,单核细胞增生李斯特菌可在冰箱(4 - 6摄氏度)中繁殖。巴氏杀菌可将生牛奶中的细菌数量降至对人类健康不构成明显风险的水平。该感染发病率相对较低,但病死率较高。风险最大的人群是孕妇和未出生婴儿、酗酒者、药物滥用者、糖尿病患者、接受改变其自然免疫力治疗的患者、艾滋病患者以及老年人。各国的监测系统应在地方、国家和国际层面由血清学、噬菌体分型及其他分型参考实验室网络的支持下,监测人类李斯特菌病的散发病例和疫情。工作组就公共卫生当局和食品行业采取行动以控制和预防这些感染提出了建议。

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