Prokšová M, Bavlovič J, Klimentová J, Pejchal J, Stulík J
Epidemiol Mikrobiol Imunol. 2019 Spring;68(2):82-89.
Tularemia, otherwise known as “rabbit fever”, is a zoonotic disease caused by a gram-negative intracellular bacterium - Francisella tularensis. The species is considered as a potential bioterrorism agent due to its high infectivity, the fact of being relatively easy to culture, the absence of human vaccine, and the potential for spreading through aerosol. In the Czech Republic, infection is usually caused by a tick bite, less frequently by a mosquito bite, direct contact with infected animals, or ingestion of contaminated water. The aim of this review is to provide a comprehensive view of tularemia, its diagnosis, clinical symptoms and treatment, along with the military perspective on a potential risk of F. tularensis to be misused as a biological weapon.
兔热病，又称“野兔热”，是一种由革兰氏阴性细胞内细菌——土拉弗朗西斯菌引起的人畜共患病。由于该菌种具有高传染性、相对易于培养、缺乏人类疫苗以及有通过气溶胶传播的可能性，它被视为一种潜在的生物恐怖主义制剂。在捷克共和国，感染通常由蜱虫叮咬引起，较少由蚊虫叮咬、直接接触受感染动物或摄入受污染的水导致。本综述的目的是全面介绍兔热病、其诊断、临床症状和治疗方法，以及从军事角度看待土拉弗朗西斯菌被滥用为生物武器的潜在风险。
