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系统性硬化症的口腔表现:一项病例对照研究。

Oral features of systemic sclerosis: A case-control study.

机构信息

Oral Medicine Unit, Departamento de Clínica e Odontologia Preventiva, Universidade Federal de Pernambuco, Recife, Brazil.

UCL Eastman Dental Institute, London, UK.

出版信息

Oral Dis. 2019 Nov;25(8):1995-2002. doi: 10.1111/odi.13174. Epub 2019 Sep 13.

Abstract

OBJECTIVE

The aim of this study was to evaluate the orofacial parameters of systemic sclerosis (SSc) and its related systemic features.

SUBJECTS AND METHODS

A descriptive case-control study was performed from November 2015 to October 2016. Ninety-three individuals were included and divided into SSc group (n = 50) and healthy controls (C, n = 43).

RESULTS

Systemic sclerosis individuals were mostly women (43/50, 86%), with a mean age of 46 years (±11.6 years). Telangiectasia (42/50, 84%) and reduced mouth opening (35/50, 70%) were the most frequent orofacial findings. The periodontitis frequency was much higher in SSc individuals than in healthy controls (90.7% × 48.83%; p < .001). In addition, SSc individuals presented a distinctive pattern of periodontitis, with low probing pocket depth (2 ± 0.65 mm × 2 ± 0.24; p < .001), higher gingival recession (4 ± 2.13 × 0.14 ± 0,22; p < .001), higher periodontal attachment loss (6 ± 1.34 mm × 2 ± 0.43, p < .001), and lower gingival bleeding index values (7.05 ± 7.25 × 21.57 ± 15.66; p < .001).

CONCLUSIONS

Orofacial manifestations were common in SSc and included a unique pattern of periodontal manifestation, characterized by lower gingival bleeding index, higher periodontal attachment loss, and low probing depth.

摘要

目的

本研究旨在评估系统性硬化症(SSc)的口面参数及其相关系统特征。

对象与方法

这是一项 2015 年 11 月至 2016 年 10 月进行的描述性病例对照研究。共纳入 93 名参与者,分为 SSc 组(n=50)和健康对照组(C 组,n=43)。

结果

SSc 患者多为女性(43/50,86%),平均年龄为 46 岁(±11.6 岁)。最常见的口面表现为毛细血管扩张(42/50,84%)和张口受限(35/50,70%)。SSc 患者的牙周炎发生率明显高于健康对照组(90.7%×48.83%;p<0.001)。此外,SSc 患者表现出一种独特的牙周炎模式,其探诊深度较浅(2±0.65mm×2±0.24mm;p<0.001),牙龈退缩程度较高(4±2.13mm×0.14±0.22mm;p<0.001),牙周附着丧失较多(6±1.34mm×2±0.43mm;p<0.001),牙龈出血指数值较低(7.05±7.25mm×21.57±15.66mm;p<0.001)。

结论

口面表现常见于 SSc,包括牙周表现的独特模式,其特点是牙龈出血指数较低、牙周附着丧失较多、探诊深度较浅。

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