Papalimperi Athanasia H, Athanaselis Sotirios A, Mina Areti D, Papoutsis Ioannis I, Spiliopoulou Chara A, Papadodima Stavroula A
Department of Forensic Medicine and Toxicology, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Exp Ther Med. 2019 Sep;18(3):2299-2306. doi: 10.3892/etm.2019.7787. Epub 2019 Jul 17.
Driving under the influence of alcohol and/or psychoactive substances increases the risk of severe, even fatal motor vehicle accidents. The aim of this descriptive study was to present the impact of alcohol and/or psychoactive substances on fatal road traffic accidents (RTAs) during the period 2011-2017. For this purpose, the toxicological investigation reports from the Department of Forensic Medicine and Toxicology of the University of Athens were used. In total, 1,841 (32.2%) of the autopsies conducted by the Department of Forensic Medicine and Toxicology of the National and Kapodistrian University of Athens over a 7-year period (2011-2017) were victims of fatal RTAs. Blood and urine samples were collected and analyzed for the presence of alcohol and psychoactive substances. The results were classified according to sex, age, victim (car driver, motorcyclist, pedestrian, or passenger) and the date the accident occurred (day, month and year). In total, 40.7% of the RTA-related fatalities were associated with alcohol consumption, among which 20.3% were car drivers. Of these, 87.3% were male victims. A higher frequency of RTA-related fatalities associated with a blood alcohol concentration (BAC) >110 mg/dl was encountered in younger compared with older age groups. Psychoactive substances were detected in 348 (18.9%) of the victims (cannabis in 46.6% of these, benzodiazepines in 25.9%, opiates in 16.4% and cocaine in 11.1% of these). The percentage of the RTA-related victims that had consumed alcohol in combination with other psychoactive substances was 4.5%. On the whole, the findings of this study suggest that alcohol and psychoactive substances are probably risk factors for RTA-related fatalities.
在酒精和/或精神活性物质影响下驾驶会增加发生严重甚至致命机动车事故的风险。这项描述性研究的目的是呈现2011年至2017年期间酒精和/或精神活性物质对致命道路交通事故(RTA)的影响。为此,使用了雅典大学法医学与毒理学系的毒理学调查报告。在国立和卡波季斯特里亚大学雅典分校法医学与毒理学系进行的为期7年(2011年至2017年)的尸检中,共有1841例(32.2%)是致命RTA的受害者。采集血液和尿液样本并分析其中酒精和精神活性物质的存在情况。结果根据性别、年龄、受害者类型(汽车驾驶员、摩托车手、行人或乘客)以及事故发生日期(日、月和年)进行分类。在与RTA相关的死亡案例中,总计40.7%与饮酒有关,其中20.3%是汽车驾驶员。在这些案例中,87.3%是男性受害者。与老年人群相比,在年轻人群中遇到的与血液酒精浓度(BAC)>110mg/dl相关的RTA相关死亡频率更高。在348例(18.9%)受害者中检测到精神活性物质(其中46.6%为大麻,25.9%为苯二氮䓬类药物,16.4%为阿片类药物,11.1%为可卡因)。同时摄入酒精和其他精神活性物质的RTA相关受害者比例为4.5%。总体而言,本研究结果表明酒精和精神活性物质可能是RTA相关死亡的风险因素。