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基于全水凝胶微流控的超拉伸和无线生物电子学。

Ultrastretchable and Wireless Bioelectronics Based on All-Hydrogel Microfluidics.

机构信息

Department of Biomedical Engineering, School of Medicine, Shenzhen University, Shenzhen, Guangdong, 518000, China.

College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong, 518000, China.

出版信息

Adv Mater. 2019 Sep;31(39):e1902783. doi: 10.1002/adma.201902783. Epub 2019 Aug 16.

Abstract

Hydrogel bioelectronics that can interface biological tissues and flexible electronics is at the core of the growing field of healthcare monitoring, smart drug systems, and wearable and implantable devices. Here, a simple strategy is demonstrated to prototype all-hydrogel bioelectronics with embedded arbitrary conductive networks using tough hydrogels and liquid metal. Due to their excellent stretchability, the resultant all-hydrogel bioelectronics exhibits stable electrochemical properties at large tensile stretch and various modes of deformation. The potential of fabricated all-hydrogel bioelectronics is demonstrated as wearable strain sensors, cardiac patches, and near-field communication (NFC) devices for monitoring various physiological conditions wirelessly. The presented simple platform paves the way of implantable hydrogel electronics for Internet-of-Things and tissue-machine interfacing applications.

摘要

水凝胶生物电子学可以实现生物组织与柔性电子之间的接口,是医疗监测、智能药物系统、可穿戴和可植入设备等领域不断发展的核心。在这里,展示了一种简单的策略,使用坚韧的水凝胶和液态金属来制作具有嵌入式任意导电网络的原型全水凝胶生物电子学。由于其出色的拉伸性,所得到的全水凝胶生物电子学在大拉伸和各种变形模式下都表现出稳定的电化学性能。所制备的全水凝胶生物电子学的潜力还体现在可穿戴应变传感器、心脏贴片和近场通信(NFC)设备上,可用于无线监测各种生理状况。所提出的简单平台为物联网和组织-机器接口应用铺平了可植入水凝胶电子学的道路。

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