Consoli S M, Safar M E
Centre de diagnostic, hôpital Broussais, Paris.
Arch Mal Coeur Vaiss. 1988 Jun;81 Spec No:145-50.
The files of 4614 hypertensive patients monitored by general practitioners (GP) were methodically analyzed. 49 p. 100 of these subjects had received no previous treatment. The protocol consisted of obligatory consultations 2, 6 and 12 months after inclusion, and questionnaires requiring specific answers, designed to describe the patient-practitioner relationship. The GP provided a psychological evaluation upon inclusion. Four main compliance classes were defined according to the data collected over 12 months: patients present at all times of the study and scrupulously respecting the medical prescription (class A: 36 p. 100 of the studied population) or neglecting the prescription (B: 33 p. 100), patients omitting one or several appointments but reestablishing contact (C: 2 p. 100) and patients lost to follow-up (D: 18 p. 100). Blood pressure parameters were better in class A as of the consultation at 2 months (ANOVA). Paradoxically, a self-assured, outgoing, serene character is a prediction factor for less satisfactory compliance than a passive, hesitant, reserved, worried character. GP behaviors were classified into homogeneous groups by principal component factorial analysis: positive prognosis factors as regards compliance are an attitude of "building up confidence" (reassuring the patient, announcing that treatment will allow him to relax, evoking possible side-effects in advance) or "medicalization of hypertension" (presented as a pathology rather than merely as a risk factor, with life-long treatment as a corollary). On the other hand, a poor prognosis factor is an attitude of "dramatization" (frightening the patient). "Building up confidence" is linked to better compliance, whatever the associated risk factors. This study statistically confirms the role of the patient-practitioner relationship in compliance.
对由全科医生(GP)监测的4614名高血压患者的档案进行了系统分析。这些患者中49%此前未接受过治疗。研究方案包括在纳入研究后2个月、6个月和12个月进行强制会诊,以及设计要求给出具体答案的问卷,以描述医患关系。全科医生在纳入研究时进行了心理评估。根据12个月内收集的数据定义了四个主要的依从性类别:在研究的所有时间段均到场并严格遵守医嘱的患者(A类:占研究人群的36%)或忽视医嘱的患者(B类:占33%),错过一次或几次预约但重新建立联系的患者(C类:占2%)以及失访患者(D类:占18%)。从2个月会诊时起,A类患者的血压参数更好(方差分析)。矛盾的是,自信、外向、平静性格的患者比被动、犹豫、内向、焦虑性格的患者依从性更差,这是一个预测因素。通过主成分因子分析将全科医生的行为分类为同质组:关于依从性的积极预后因素是“建立信心”的态度(让患者放心,告知治疗会让他放松,提前提及可能的副作用)或“高血压医学化”(将其视为一种疾病而非仅仅是一个风险因素,并将终身治疗作为必然结果)。另一方面,不良预后因素是“戏剧化”的态度(吓唬患者)。无论相关风险因素如何,“建立信心”都与更好的依从性相关。这项研究从统计学上证实了医患关系在依从性方面的作用。