Morgan-Capner P, Wright J, Miller C L, Miller E
Preston Public Health Laboratory.
BMJ. 1988 Sep 24;297(6651):770-2. doi: 10.1136/bmj.297.6651.770.
Before the introduction of measles, mumps, and rubella vaccine a survey was carried out to measure antibody prevalence to the three viruses by age. A total of 8716 samples of serum collected by five public health laboratories in different parts of England during 1986-7 were tested. Despite the current measles vaccination programme 60% of children aged 1-2 years did not have measles antibody and over 80% did not have antibodies to mumps and rubella. In the 3-4 year age group 17% of the children were susceptible to measles, 55% to mumps, and 73% to rubella. The results suggest that vaccinating children early in the second year of life will be necessary to eliminate the three diseases. The survey provides baseline data for continuing surveillance of the immediate and long term effects of the new vaccination strategy.
在引入麻疹、腮腺炎和风疹疫苗之前，开展了一项调查以按年龄测量对这三种病毒的抗体流行率。对1986 - 1987年期间英格兰不同地区的五个公共卫生实验室收集的总共8716份血清样本进行了检测。尽管目前有麻疹疫苗接种计划，但1 - 2岁的儿童中有60%没有麻疹抗体，超过80%没有腮腺炎和风疹抗体。在3 - 4岁年龄组中，17%的儿童对麻疹易感，55%对腮腺炎易感，73%对风疹易感。结果表明，为消除这三种疾病，有必要在儿童生命的第二年尽早进行疫苗接种。该调查为持续监测新疫苗接种策略的近期和长期效果提供了基线数据。
