英格兰诺沃克病毒抗体的流行情况：使用杆状病毒表达的诺沃克病毒衣壳抗原通过酶联免疫吸附测定法进行检测
Prevalence of antibodies to Norwalk virus in England: detection by enzyme-linked immunosorbent assay using baculovirus-expressed Norwalk virus capsid antigen.
作者信息
Gray J J, Jiang X, Morgan-Capner P, Desselberger U, Estes M K
机构信息
Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom.
出版信息
J Clin Microbiol. 1993 Apr;31(4):1022-5. doi: 10.1128/jcm.31.4.1022-1025.1993.
Abstract
A total of 3,250 serum specimens collected in England in 1991 and 1992 were tested by an indirect enzyme-linked immunosorbent assay for antibody to Norwalk virus using baculovirus-expressed capsid antigen, and 2,382 (73.3%) were positive. The prevalence of Norwalk virus antibody differed regionally. It was lowest (24.6%) in 6- to 11-month-old infants and increased to 89.7% in persons over 60 years old.
摘要
1991年和1992年在英国采集的总共3250份血清样本，采用杆状病毒表达的衣壳抗原，通过间接酶联免疫吸附测定法检测诺沃克病毒抗体，其中2382份（73.3%）呈阳性。诺沃克病毒抗体的流行率存在地区差异。在6至11个月大的婴儿中最低（24.6%），在60岁以上人群中升至89.7%。
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