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1
Prevalence of antibodies to Norwalk virus in England: detection by enzyme-linked immunosorbent assay using baculovirus-expressed Norwalk virus capsid antigen.英格兰诺沃克病毒抗体的流行情况：使用杆状病毒表达的诺沃克病毒衣壳抗原通过酶联免疫吸附测定法进行检测
J Clin Microbiol. 1993 Apr;31(4):1022-5. doi: 10.1128/jcm.31.4.1022-1025.1993.
2
Detection of immunoglobulin M (IgM), IgA, and IgG Norwalk virus-specific antibodies by indirect enzyme-linked immunosorbent assay with baculovirus-expressed Norwalk virus capsid antigen in adult volunteers challenged with Norwalk virus.在接受诺如病毒攻击的成年志愿者中，通过使用杆状病毒表达的诺如病毒衣壳抗原的间接酶联免疫吸附测定法检测免疫球蛋白M（IgM）、IgA和IgG诺如病毒特异性抗体。
J Clin Microbiol. 1994 Dec;32(12):3059-63. doi: 10.1128/jcm.32.12.3059-3063.1994.
3
Prevalence of antibodies to human caliciviruses (HuCVs) in Kuwait established by ELISA using baculovirus-expressed capsid antigens representing two genogroups of HuCVs.采用杆状病毒表达的代表人类杯状病毒（HuCVs）两个基因组的衣壳抗原，通过酶联免疫吸附测定法（ELISA）确定科威特人群中HuCVs抗体的流行率。
J Med Virol. 1997 Feb;51(2):115-8.
4
Epidemiological study of Norwalk virus infections in Japan and Southeast Asia by enzyme-linked immunosorbent assays with Norwalk virus capsid protein produced by the baculovirus expression system.利用杆状病毒表达系统产生的诺如病毒衣壳蛋白，通过酶联免疫吸附测定法对日本和东南亚诺如病毒感染进行的流行病学研究。
J Clin Microbiol. 1994 Jan;32(1):121-6. doi: 10.1128/jcm.32.1.121-126.1994.
5
Comparison of the reactivities of baculovirus-expressed recombinant Norwalk virus capsid antigen with those of the native Norwalk virus antigen in serologic assays and some epidemiologic observations.杆状病毒表达的重组诺沃克病毒衣壳抗原与天然诺沃克病毒抗原在血清学检测中的反应性比较及一些流行病学观察。
J Clin Microbiol. 1993 Aug;31(8):2185-91. doi: 10.1128/jcm.31.8.2185-2191.1993.
6
Detection of antibody to recombinant Norwalk virus antigen in specimens from outbreaks of gastroenteritis.在胃肠炎暴发病例标本中检测重组诺沃克病毒抗原抗体
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7
Identification of an epitope common to genogroup 1 "norwalk-like viruses".确定基因组1型“诺如病毒样病毒”的共同表位
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Antigenic diversity of Norwalk-like viruses: expression of the capsid protein of a genogroup I virus, distantly related to Norwalk virus.诺如病毒样病毒的抗原多样性：与诺瓦克病毒亲缘关系较远的基因组I型病毒衣壳蛋白的表达
Arch Virol. 2000;145(4):711-23. doi: 10.1007/s007050050665.
9
Antibody prevalence and immunoglobulin IgG subclass pattern to Norwalk virus in Sweden.瑞典人群中针对诺如病毒的抗体流行率及免疫球蛋白IgG亚类模式
J Med Virol. 1995 Sep;47(1):52-7. doi: 10.1002/jmv.1890470111.
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Seroprevalence against Norwalk-like human caliciviruses in beijing, China.中国北京地区针对诺如病毒样人杯状病毒的血清流行率。
J Med Virol. 2000 Jan;60(1):97-101. doi: 10.1002/(sici)1096-9071(200001)60:1<97::aid-jmv16>3.0.co;2-d.

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Family income and exposure to norovirus in childhood: Findings from the UK Millennium Cohort Study.家庭收入与儿童时期诺如病毒暴露情况：英国千禧队列研究的结果
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10
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本文引用的文献

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Comparative study of the acquisition of antibody to Norwalk virus in pediatric populations.儿科人群中诺如病毒抗体获得情况的比较研究。
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Age-specific prevalence of antibody to rotavirus, Escherichia coli heat-labile enterotoxin, Norwalk virus, and hepatitis A virus in a rural community in Thailand.泰国某农村社区中轮状病毒、大肠杆菌不耐热肠毒素、诺沃克病毒及甲型肝炎病毒抗体的年龄特异性流行率。
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Diarrhea among infants and young children in Canada: a longitudinal study in three northern communities.加拿大婴幼儿腹泻情况：对三个北部社区的纵向研究
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Detection by immune electron microscopy of the Snow Mountain agent of acute viral gastroenteritis.用免疫电子显微镜检测急性病毒性肠胃炎的雪山因子。
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Diarrhea due to Norwalk virus in families.家庭中由诺如病毒引起的腹泻
J Infect Dis. 1982 Jul;146(1):116-7. doi: 10.1093/infdis/146.1.116.
6
Acquisition of serum antibody to Norwalk Virus and rotavirus and relation to diarrhea in a longitudinal study of young children in rural Bangladesh.在孟加拉国农村幼儿的一项纵向研究中，诺如病毒和轮状病毒血清抗体的获得及其与腹泻的关系。
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Visualization by immune electron microscopy of a 27-nm particle associated with acute infectious nonbacterial gastroenteritis.通过免疫电子显微镜观察到与急性感染性非细菌性肠胃炎相关的一种27纳米颗粒。
J Virol. 1972 Nov;10(5):1075-81. doi: 10.1128/JVI.10.5.1075-1081.1972.
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Surveillance of antibody to measles, mumps, and rubella by age.按年龄对麻疹、腮腺炎和风疹抗体进行监测。
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10
Evidence of immunity induced by naturally acquired rotavirus and Norwalk virus infection on two remote Panamanian islands.巴拿马两个偏远岛屿上自然获得的轮状病毒和诺如病毒感染所诱导的免疫证据。
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英格兰诺沃克病毒抗体的流行情况：使用杆状病毒表达的诺沃克病毒衣壳抗原通过酶联免疫吸附测定法进行检测

Prevalence of antibodies to Norwalk virus in England: detection by enzyme-linked immunosorbent assay using baculovirus-expressed Norwalk virus capsid antigen.

作者信息

Gray J J, Jiang X, Morgan-Capner P, Desselberger U, Estes M K

机构信息

Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, United Kingdom.

出版信息

J Clin Microbiol. 1993 Apr;31(4):1022-5. doi: 10.1128/jcm.31.4.1022-1025.1993.

DOI:10.1128/jcm.31.4.1022-1025.1993
PMID:8385148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC263611/
Abstract

A total of 3,250 serum specimens collected in England in 1991 and 1992 were tested by an indirect enzyme-linked immunosorbent assay for antibody to Norwalk virus using baculovirus-expressed capsid antigen, and 2,382 (73.3%) were positive. The prevalence of Norwalk virus antibody differed regionally. It was lowest (24.6%) in 6- to 11-month-old infants and increased to 89.7% in persons over 60 years old.

摘要

1991年和1992年在英国采集的总共3250份血清样本，采用杆状病毒表达的衣壳抗原，通过间接酶联免疫吸附测定法检测诺沃克病毒抗体，其中2382份（73.3%）呈阳性。诺沃克病毒抗体的流行率存在地区差异。在6至11个月大的婴儿中最低（24.6%），在60岁以上人群中升至89.7%。